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The studies were performed on 161 patients with allergosis, aged 18 to 60 years. The severity of allergosis was the most significant clinical sign affecting the pain sensitivity of the patients under study. All the patients with allergoses were characterized by a higher psychoemotional response to pain stimuli than patients without the accompanying pathology. The patients with severe clinical signs of allergosis in history were characterized by hyperalgesia, while those with moderate allergosis were characterized by hypoalgesia. In patients with severe allergosis afferent signals processing in the central nervous system was disturbed. The differences in pain sensitivity in two groups of patients suggest different approaches to the selection of analgesia technique.
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