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A 59-year-old man had explosive watery diarrhoea, tendency towards collapse, flushes and aphonia. Pre-operative serum concentrations of vasoactive intestinal polypeptide (VIP) were up to 1030 ng/l, those of gastric inhibitory polypeptide (GIP) up to 2675 ng/l, as measured by radioimmunoassay. Cross-reaction by antisera used in the radioimmunoassay were excluded. Pancreatic tumour was diagnosed by ultrasound and by elective coeliac arteriography. After excision the abnormal fidings disappeared as did the symptoms. Biological half-life of plasma-VIP (determined during removal of the tumour from plasma samples by radioimmunoassay) was about 45 minutes. The tumour produced both VIP and GIP.
H Kunert, and
F M Kuhn, and
K Schwemmle, and
R Ottenjann
January 1979,
Acta medica Scandinavica,
H Kunert, and
F M Kuhn, and
K Schwemmle, and
R Ottenjann
January 1976,
Clinical endocrinology,
H Kunert, and
F M Kuhn, and
K Schwemmle, and
R Ottenjann
January 1979,
Scandinavian journal of gastroenterology. Supplement,
H Kunert, and
F M Kuhn, and
K Schwemmle, and
R Ottenjann
November 1975,
Klinicheskaia meditsina,
H Kunert, and
F M Kuhn, and
K Schwemmle, and
R Ottenjann
May 1975,
Wiadomosci lekarskie (Warsaw, Poland : 1960),
H Kunert, and
F M Kuhn, and
K Schwemmle, and
R Ottenjann
October 1981,
Ugeskrift for laeger,
H Kunert, and
F M Kuhn, and
K Schwemmle, and
R Ottenjann
May 1975,
Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen,
H Kunert, and
F M Kuhn, and
K Schwemmle, and
R Ottenjann
April 1979,
La Nouvelle presse medicale,
H Kunert, and
F M Kuhn, and
K Schwemmle, and
R Ottenjann
June 1977,
L'union medicale du Canada,
H Kunert, and
F M Kuhn, and
K Schwemmle, and
R Ottenjann
January 1982,
Digestion,
