Histamine antagonists; an experimental and clinical study of N,N-dimethyl-N'-2-thiazolyl-N'-p-methoxybenzyl-ethylenediamine hydrochloride (194-B).
1949
T B BERNSTEIN, and
S M FEINBERG
UI
MeSH Term
Description
Entries
D005029
Ethylenediamines
Derivatives of ethylenediamine (the structural formula NH2CH2CH2NH2).
D006632
Histamine
An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only.