Biomaterial Database

Efficacy of Ledermix paste in eliminating Staphylococcus aureus from infected dentinal tubules in vitro. 1991

I Heling, and M Pecht

Department of Endodontics, Hadassah-Hebrew University, Jerusalem, Israel.

The efficacy of Ledermix paste in disinfection of dentinal tubules was studied in a model developed by Haapasalo and Orstavik with some modifications. Ledermix and 3% Tetracycline in a hydrous base were effective in reducing the amount of Staphylococcus aureus in dentinal tubules after 7 days of incubation and also after recontamination. They were not effective after 24 h.

UI	MeSH Term	Description	Entries
D002417	Cattle	Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.	Beef Cow,Bos grunniens,Bos indicus,Bos indicus Cattle,Bos taurus,Cow,Cow, Domestic,Dairy Cow,Holstein Cow,Indicine Cattle,Taurine Cattle,Taurus Cattle,Yak,Zebu,Beef Cows,Bos indicus Cattles,Cattle, Bos indicus,Cattle, Indicine,Cattle, Taurine,Cattle, Taurus,Cattles, Bos indicus,Cattles, Indicine,Cattles, Taurine,Cattles, Taurus,Cow, Beef,Cow, Dairy,Cow, Holstein,Cows,Dairy Cows,Domestic Cow,Domestic Cows,Indicine Cattles,Taurine Cattles,Taurus Cattles,Yaks,Zebus
D002733	Chlorophenols	Phenols substituted with one or more chlorine atoms in any position.	Chlorophenol,Hydroxychlorobenzenes
D003707	Demeclocycline	A TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.	Demethylchlortetracycline,Declomycin,Demeclocycline Hydrochloride,Demeclocycline Monohydrochloride,Demeclocycline, 4-epimer,Demeclocycline, Calcium (1:1) Salt,Demeclocycline, Calcium (1:2) Salt,Ledermycin,Lédermycine,Hydrochloride, Demeclocycline,Monohydrochloride, Demeclocycline
D003804	Dentin	The hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root, which is harder and denser than bone but softer than enamel, and is thus readily abraded when left unprotected. (From Jablonski, Dictionary of Dentistry, 1992)	Dentine,Dentines,Dentins
D004338	Drug Combinations	Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture.	Drug Combination,Combination, Drug,Combinations, Drug
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012388	Root Canal Irrigants	Chemicals used mainly to disinfect root canals after pulpectomy and before obturation. The major ones are camphorated monochlorophenol, EDTA, formocresol, hydrogen peroxide, metacresylacetate, and sodium hypochlorite. Root canal irrigants include also rinsing solutions of distilled water, sodium chloride, etc.	Root Canal Irrigant,Root Canal Medicament,Root Canal Medicaments,Canal Irrigant, Root,Canal Irrigants, Root,Canal Medicament, Root,Canal Medicaments, Root,Irrigant, Root Canal,Irrigants, Root Canal,Medicament, Root Canal,Medicaments, Root Canal
D013211	Staphylococcus aureus	Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.
D013752	Tetracycline	A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.	4-Epitetracycline,Achromycin,Achromycin V,Hostacyclin,Sustamycin,Tetrabid,Tetracycline Hydrochloride,Tetracycline Monohydrochloride,Topicycline,4 Epitetracycline
D014222	Triamcinolone Acetonide	An esterified form of TRIAMCINOLONE. It is an anti-inflammatory glucocorticoid used topically in the treatment of various skin disorders. Intralesional, intramuscular, and intra-articular injections are also administered under certain conditions.	Azmacort,Cinonide,Kenacort A,Kenalog,Kenalog 40,Tricort-40,Acetonide, Triamcinolone,Tricort 40,Tricort40