Biomaterial Database

Efficacy of three cavity liners in eliminating bacteria from infected dentinal tubules. 1995

N P Chandler, and I Heling

Department of Restorative Dentistry, University of Otago, School of Dentistry, Dunedin, New Zealand.

Three lining materials, Life, Ketac-Bond, and IRM, were investigated for their antibacterial effects within dentinal tubules. Sterile saline served as control. Sixty standardized bovine root specimens were infected with Enterococcus faecalis following smear layer removal. The materials were mixed according to manufacturer's directions and inserted in the canal lumina; additional IRM specimens received a softer than normal mix. Specimens were incubated for 24 hours or 7 days, after which dentinal samples were taken from within the lumina and the numbers of bacteria present were assessed. All the materials had a significant antibacterial effect after 7 days. Life demonstrated a more marked effect at 7 days than at 24 hours. The strongest antibacterial effect at 24 hours was shown by a "soft" mix of IRM. Ketac-Bond demonstrated an increase in antibacterial activity during the experimental period.

UI	MeSH Term	Description	Entries
D008768	Methylmethacrylates	The methyl esters of methacrylic acid that polymerize easily and are used as tissue cements, dental materials, and absorbent for biological substances.
D008826	Microbial Sensitivity Tests	Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).	Bacterial Sensitivity Tests,Drug Sensitivity Assay, Microbial,Minimum Inhibitory Concentration,Antibacterial Susceptibility Breakpoint Determination,Antibiogram,Antimicrobial Susceptibility Breakpoint Determination,Bacterial Sensitivity Test,Breakpoint Determination, Antibacterial Susceptibility,Breakpoint Determination, Antimicrobial Susceptibility,Fungal Drug Sensitivity Tests,Fungus Drug Sensitivity Tests,Sensitivity Test, Bacterial,Sensitivity Tests, Bacterial,Test, Bacterial Sensitivity,Tests, Bacterial Sensitivity,Viral Drug Sensitivity Tests,Virus Drug Sensitivity Tests,Antibiograms,Concentration, Minimum Inhibitory,Concentrations, Minimum Inhibitory,Inhibitory Concentration, Minimum,Inhibitory Concentrations, Minimum,Microbial Sensitivity Test,Minimum Inhibitory Concentrations,Sensitivity Test, Microbial,Sensitivity Tests, Microbial,Test, Microbial Sensitivity,Tests, Microbial Sensitivity
D002126	Calcium Hydroxide	A white powder prepared from lime that has many medical and industrial uses. It is in many dental formulations, especially for root canal filling.	Hydroxide, Calcium
D002417	Cattle	Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.	Beef Cow,Bos grunniens,Bos indicus,Bos indicus Cattle,Bos taurus,Cow,Cow, Domestic,Dairy Cow,Holstein Cow,Indicine Cattle,Taurine Cattle,Taurus Cattle,Yak,Zebu,Beef Cows,Bos indicus Cattles,Cattle, Bos indicus,Cattle, Indicine,Cattle, Taurine,Cattle, Taurus,Cattles, Bos indicus,Cattles, Indicine,Cattles, Taurine,Cattles, Taurus,Cow, Beef,Cow, Dairy,Cow, Holstein,Cows,Dairy Cows,Domestic Cow,Domestic Cows,Indicine Cattles,Taurine Cattles,Taurus Cattles,Yaks,Zebus
D003736	Dental Cavity Lining	An inner coating, as of varnish or other protective substance, to cover the dental cavity wall. It is usually a resinous film-forming agent dissolved in a volatile solvent, or a suspension of calcium hydroxide in a solution of a synthetic resin. The lining seals the dentinal tubules and protects the pulp before a restoration is inserted. (Jablonski, Illustrated Dictionary of Dentistry, 1982)	Varnish, Cavity,Cavity Liner, Dental,Cavity Lining Varnish,Cavity Lining Varnishes,Cavity Lining, Dental,Cavity Linings, Dental,Cavity Varnishes,Dental Cavity Liner,Dental Cavity Liners,Dental Cavity Linings,Liners, Dental Cavity,Lining, Dental Cavity,Linings, Dental Cavity,Cavity Liners, Dental,Cavity Varnish,Liner, Dental Cavity,Varnish, Cavity Lining,Varnishes, Cavity,Varnishes, Cavity Lining
D003764	Dental Materials	Materials used in the production of dental bases, restorations, impressions, prostheses, etc.	Dental Material,Material, Dental,Materials, Dental
D003804	Dentin	The hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root, which is harder and denser than bone but softer than enamel, and is thus readily abraded when left unprotected. (From Jablonski, Dictionary of Dentistry, 1992)	Dentine,Dentines,Dentins
D004203	Disinfection	Rendering pathogens harmless through the use of heat, antiseptics, antibacterial agents, etc.
D005899	Glass Ionomer Cements	A polymer obtained by reacting polyacrylic acid with a special anion-leachable glass (alumino-silicate). The resulting cement is more durable and tougher than others in that the materials comprising the polymer backbone do not leach out.	Glass Ionomer Cement,Glass Polyalkenoate Cement,Polyalkenoate Cement,Polyalkenoate Cements,Glass Polyalkenoate Cements,Glass-Ionomer Cement,Cement, Glass Ionomer,Cement, Glass Polyalkenoate,Cement, Glass-Ionomer,Cement, Polyalkenoate,Cements, Glass Ionomer,Cements, Glass Polyalkenoate,Cements, Glass-Ionomer,Cements, Polyalkenoate,Glass-Ionomer Cements,Ionomer Cement, Glass,Polyalkenoate Cement, Glass
D000704	Analysis of Variance	A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.	ANOVA,Analysis, Variance,Variance Analysis,Analyses, Variance,Variance Analyses