Bone mineral density in Indian women with rheumatoid arthritis. 2009

Subramanian Shankar, and Rohini Handa, and Ritu Aneja, and Vishal Marwaha, and A C Ammini, and V Aprajita
All India Institute of Medical Sciences, New Delhi, India.

Osteoporosis (OP) is being increasingly recognized in inflammatory rheumatic diseases like rheumatoid arthritis (RA). Ethnicity influences bone mineral density (BMD) and fracture risk. Due to paucity of data on this aspect of RA from Asian countries including India, we prospectively studied 84 premenopausal women with RA of at least 2 years duration and 247 healthy, age (within 5 years) and sex-matched controls. A significant difference in BMD between patients and controls was observed only at the femoral neck. As many as 22% patients with RA exhibited osteoporosis at least one site in contrast to 9% controls. Nearly 40% of patients exhibited osteopenia at all the three sites. Modified Sharp score, disease duration and DMARD naive period were found to correlate with low BMD. However, on multivariate analysis, only modified Sharp score was shown to be significantly associated with low BMD. Our study draws attention to the poor bone health in Asian Indian women with RA.

UI MeSH Term Description Entries
D007194 India A country in southern Asia, bordering the Arabian Sea and the Bay of Bengal, between Burma and Pakistan. The capitol is New Delhi. Republic of India
D007391 International Cooperation The interaction of persons or groups of persons representing various nations in the pursuit of a common goal or interest. Foreign Aid,Treaties,Aid, Foreign,Cooperation, International,Treaty
D008159 Lumbar Vertebrae VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE. Vertebrae, Lumbar
D010024 Osteoporosis Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. Age-Related Osteoporosis,Bone Loss, Age-Related,Osteoporosis, Age-Related,Osteoporosis, Post-Traumatic,Osteoporosis, Senile,Senile Osteoporosis,Osteoporosis, Involutional,Age Related Osteoporosis,Age-Related Bone Loss,Age-Related Bone Losses,Age-Related Osteoporoses,Bone Loss, Age Related,Bone Losses, Age-Related,Osteoporoses,Osteoporoses, Age-Related,Osteoporoses, Senile,Osteoporosis, Age Related,Osteoporosis, Post Traumatic,Post-Traumatic Osteoporoses,Post-Traumatic Osteoporosis,Senile Osteoporoses
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D011859 Radiography Examination of any part of the body for diagnostic purposes by means of X-RAYS or GAMMA RAYS, recording the image on a sensitized surface (such as photographic film). Radiology, Diagnostic X-Ray,Roentgenography,X-Ray, Diagnostic,Diagnostic X-Ray,Diagnostic X-Ray Radiology,X-Ray Radiology, Diagnostic,Diagnostic X Ray,Diagnostic X Ray Radiology,Diagnostic X-Rays,Radiology, Diagnostic X Ray,X Ray Radiology, Diagnostic,X Ray, Diagnostic,X-Rays, Diagnostic
D001851 Bone Diseases, Metabolic Diseases that affect the METABOLIC PROCESSES of BONE TISSUE. Low Bone Density,Low Bone Mineral Density,Osteopenia,Metabolic Bone Diseases,Bone Density, Low,Bone Disease, Metabolic,Low Bone Densities,Metabolic Bone Disease,Osteopenias
D003430 Cross-Sectional Studies Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time. Disease Frequency Surveys,Prevalence Studies,Analysis, Cross-Sectional,Cross Sectional Analysis,Cross-Sectional Survey,Surveys, Disease Frequency,Analyses, Cross Sectional,Analyses, Cross-Sectional,Analysis, Cross Sectional,Cross Sectional Analyses,Cross Sectional Studies,Cross Sectional Survey,Cross-Sectional Analyses,Cross-Sectional Analysis,Cross-Sectional Study,Cross-Sectional Surveys,Disease Frequency Survey,Prevalence Study,Studies, Cross-Sectional,Studies, Prevalence,Study, Cross-Sectional,Study, Prevalence,Survey, Cross-Sectional,Survey, Disease Frequency,Surveys, Cross-Sectional
D005260 Female Females
D005272 Femur Neck The constricted portion of the thigh bone between the femur head and the trochanters. Femoral Neck,Neck, Femoral,Neck, Femur

Related Publications

Subramanian Shankar, and Rohini Handa, and Ritu Aneja, and Vishal Marwaha, and A C Ammini, and V Aprajita
January 2002, Calcified tissue international,
Subramanian Shankar, and Rohini Handa, and Ritu Aneja, and Vishal Marwaha, and A C Ammini, and V Aprajita
April 2005, Rheumatology international,
Subramanian Shankar, and Rohini Handa, and Ritu Aneja, and Vishal Marwaha, and A C Ammini, and V Aprajita
January 2001, Scandinavian journal of rheumatology,
Subramanian Shankar, and Rohini Handa, and Ritu Aneja, and Vishal Marwaha, and A C Ammini, and V Aprajita
December 2013, International journal of rheumatic diseases,
Subramanian Shankar, and Rohini Handa, and Ritu Aneja, and Vishal Marwaha, and A C Ammini, and V Aprajita
January 2011, Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi,
Subramanian Shankar, and Rohini Handa, and Ritu Aneja, and Vishal Marwaha, and A C Ammini, and V Aprajita
January 2001, Terapevticheskii arkhiv,
Subramanian Shankar, and Rohini Handa, and Ritu Aneja, and Vishal Marwaha, and A C Ammini, and V Aprajita
February 2020, Calcified tissue international,
Subramanian Shankar, and Rohini Handa, and Ritu Aneja, and Vishal Marwaha, and A C Ammini, and V Aprajita
May 2022, JPMA. The Journal of the Pakistan Medical Association,
Subramanian Shankar, and Rohini Handa, and Ritu Aneja, and Vishal Marwaha, and A C Ammini, and V Aprajita
April 1993, Annals of the rheumatic diseases,
Subramanian Shankar, and Rohini Handa, and Ritu Aneja, and Vishal Marwaha, and A C Ammini, and V Aprajita
January 2007, Revista da Associacao Medica Brasileira (1992),
Copied contents to your clipboard!