-transparent.png){kind=logo}
We report the cytogenetic mapping of the thymidine kinase (tk-1) gene in the mouse using two complementary and independent analyses: (1) investigation of chromosome aberrations associated with tk-1 gene inactivation in the L5178Y TK+/- -3.7.2C cell line, and (2) fluorescence in situ molecular hybridization of cloned tk-1 cDNA probes to mitotic chromosomes of this cell line. The consensus location from both analyses is 11E1-E2. Consideration of the mouse tk-1 gene localization, along with evidence that the homologous human TK1 gene is located distally on the large arm of chromosome 17, appears to extend the region of homology between MMU11 and HSA17 to the distal end of both chromosomes.
J Hozier, and
J Scalzi, and
J Sawyer, and
N Carley, and
M Applegate, and
D Clive, and
M M Moore
September 1992,
Genetics,
J Hozier, and
J Scalzi, and
J Sawyer, and
N Carley, and
M Applegate, and
D Clive, and
M M Moore
November 1990,
Genomics,
J Hozier, and
J Scalzi, and
J Sawyer, and
N Carley, and
M Applegate, and
D Clive, and
M M Moore
January 1996,
Mammalian genome : official journal of the International Mammalian Genome Society,
J Hozier, and
J Scalzi, and
J Sawyer, and
N Carley, and
M Applegate, and
D Clive, and
M M Moore
July 1996,
Mammalian genome : official journal of the International Mammalian Genome Society,
J Hozier, and
J Scalzi, and
J Sawyer, and
N Carley, and
M Applegate, and
D Clive, and
M M Moore
March 1986,
The Journal of cell biology,
J Hozier, and
J Scalzi, and
J Sawyer, and
N Carley, and
M Applegate, and
D Clive, and
M M Moore
December 1997,
Mammalian genome : official journal of the International Mammalian Genome Society,
J Hozier, and
J Scalzi, and
J Sawyer, and
N Carley, and
M Applegate, and
D Clive, and
M M Moore
January 1991,
Mammalian genome : official journal of the International Mammalian Genome Society,
J Hozier, and
J Scalzi, and
J Sawyer, and
N Carley, and
M Applegate, and
D Clive, and
M M Moore
April 1990,
Genomics,
J Hozier, and
J Scalzi, and
J Sawyer, and
N Carley, and
M Applegate, and
D Clive, and
M M Moore
January 1977,
Cytogenetics and cell genetics,
J Hozier, and
J Scalzi, and
J Sawyer, and
N Carley, and
M Applegate, and
D Clive, and
M M Moore
March 1994,
Mammalian genome : official journal of the International Mammalian Genome Society,
