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We have studied the expression of mouse galactokinase in human-mouse somatic cell hybrids segregating mouse chromosomes. Since concordant segregation of the expression of mouse galactokinase and the presence of mouse chromosome 11 were observed in the hybrid clones, we conclude that the gene for mouse galactokinase is located on mouse chromosome 11. We have also investigated the expression of mouse galactokinase in somatic cell hybrids between thymidine kinase-deficient Chinese hamster cells and mouse peritoneal macrophages. The results of this study indicate that the expression of mouse galactokinase and thymidine kinase segregates concordantly, and, therefore, we infer that the gene for mouse thymidine kinase is also located on mouse chromosome 11.
P McBreen, and
K G Orkwiszewski, and
C J Chern, and
W J Mellman, and
C M Croce
June 1977,
Human genetics,
P McBreen, and
K G Orkwiszewski, and
C J Chern, and
W J Mellman, and
C M Croce
March 1977,
Somatic cell genetics,
P McBreen, and
K G Orkwiszewski, and
C J Chern, and
W J Mellman, and
C M Croce
February 1978,
Proceedings of the National Academy of Sciences of the United States of America,
P McBreen, and
K G Orkwiszewski, and
C J Chern, and
W J Mellman, and
C M Croce
January 1975,
Cytogenetics and cell genetics,
P McBreen, and
K G Orkwiszewski, and
C J Chern, and
W J Mellman, and
C M Croce
January 1976,
Somatic cell genetics,
P McBreen, and
K G Orkwiszewski, and
C J Chern, and
W J Mellman, and
C M Croce
November 1974,
Nature,
P McBreen, and
K G Orkwiszewski, and
C J Chern, and
W J Mellman, and
C M Croce
August 1995,
Genome research,
P McBreen, and
K G Orkwiszewski, and
C J Chern, and
W J Mellman, and
C M Croce
July 1991,
Genomics,
P McBreen, and
K G Orkwiszewski, and
C J Chern, and
W J Mellman, and
C M Croce
September 1994,
Genomics,
P McBreen, and
K G Orkwiszewski, and
C J Chern, and
W J Mellman, and
C M Croce
July 1971,
Science (New York, N.Y.),
