A comparison of lactate indices during ramp exercise using modelling techniques and conventional methods. 2008

Vincent Thomas, and Frédéric Costes, and Michel Chatagnon, and Jean-Pierre Pouilly, and Thierry Busso
Laboratoire de Physiologie de l'Exercise, Université Jean Monnet de Saint-Etienne, Saint-Etienne, France.

The aim of this study was to compare the lactate indices provided by single- and double-breakpoint models with lactate thresholds obtained with conventional methods. Arterial samples for the determination of lactate concentrations were drawn from eight participants at rest and every minute during a ramp test (15 W x min(-1)) on a cycle ergometer. Lactate thresholds were determined from a blood lactate concentration equal to 4 mM (LT(4)), from an increase of 1 mM above the resting level (Delta1 mM), and from indirect methods using ventilatory parameters. Other indices were computed from the modelling of the lactate curve using an exponential function (LSI), a polynomial function (Dmax), a semi-log model (SLog), a parabola plus delay model (Mod P), and a two-breakpoint model (Mod M). Mod P and Mod M showed poor agreement with the other methods. LT(4), Dmax, LSI, and respiratory exchange ratio equal to 1 were correlated with each other (0.81 <or= R <or= 0.92) and their mean differences ranged from 2.8 to 15 W, with limits of agreement within the range +/- 24.6 to +/- 42.4 W. These results question the interest in breakpoints models to detect lactate thresholds, knowing that LT(4), LSI, Dmax, and respiratory exchange ratio equal to 1 provide indices that occur at similar power outputs.

UI MeSH Term Description Entries
D008297 Male Males
D008954 Models, Biological Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment. Biological Model,Biological Models,Model, Biological,Models, Biologic,Biologic Model,Biologic Models,Model, Biologic
D010101 Oxygen Consumption The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346) Consumption, Oxygen,Consumptions, Oxygen,Oxygen Consumptions
D005080 Exercise Test Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used. Arm Ergometry Test,Bicycle Ergometry Test,Cardiopulmonary Exercise Testing,Exercise Testing,Step Test,Stress Test,Treadmill Test,Cardiopulmonary Exercise Test,EuroFit Tests,Eurofit Test Battery,European Fitness Testing Battery,Fitness Testing,Physical Fitness Testing,Arm Ergometry Tests,Bicycle Ergometry Tests,Cardiopulmonary Exercise Tests,Ergometry Test, Arm,Ergometry Test, Bicycle,Ergometry Tests, Arm,Ergometry Tests, Bicycle,EuroFit Test,Eurofit Test Batteries,Exercise Test, Cardiopulmonary,Exercise Testing, Cardiopulmonary,Exercise Tests,Exercise Tests, Cardiopulmonary,Fitness Testing, Physical,Fitness Testings,Step Tests,Stress Tests,Test Battery, Eurofit,Test, Arm Ergometry,Test, Bicycle Ergometry,Test, Cardiopulmonary Exercise,Test, EuroFit,Test, Exercise,Test, Step,Test, Stress,Test, Treadmill,Testing, Cardiopulmonary Exercise,Testing, Exercise,Testing, Fitness,Testing, Physical Fitness,Tests, Arm Ergometry,Tests, Bicycle Ergometry,Tests, Cardiopulmonary Exercise,Tests, EuroFit,Tests, Exercise,Tests, Step,Tests, Stress,Tests, Treadmill,Treadmill Tests
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D015308 Anaerobic Threshold The oxygen consumption level above which aerobic energy production is supplemented by anaerobic mechanisms during exercise, resulting in a sustained increase in lactate concentration and metabolic acidosis. The anaerobic threshold is affected by factors that modify oxygen delivery to the tissues; it is low in patients with heart disease. Methods of measurement include direct measure of lactate concentration, direct measurement of bicarbonate concentration, and gas exchange measurements. Anaerobic Thresholds,Threshold, Anaerobic,Thresholds, Anaerobic
D015444 Exercise Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure. Aerobic Exercise,Exercise, Aerobic,Exercise, Isometric,Exercise, Physical,Isometric Exercise,Physical Activity,Acute Exercise,Exercise Training,Activities, Physical,Activity, Physical,Acute Exercises,Aerobic Exercises,Exercise Trainings,Exercise, Acute,Exercises,Exercises, Acute,Exercises, Aerobic,Exercises, Isometric,Exercises, Physical,Isometric Exercises,Physical Activities,Physical Exercise,Physical Exercises,Training, Exercise,Trainings, Exercise
D055815 Young Adult A person between 19 and 24 years of age. Adult, Young,Adults, Young,Young Adults
D019344 Lactic Acid A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Lactate,2-Hydroxypropanoic Acid,2-Hydroxypropionic Acid,Ammonium Lactate,D-Lactic Acid,L-Lactic Acid,Propanoic Acid, 2-Hydroxy-, (2R)-,Propanoic Acid, 2-Hydroxy-, (2S)-,Sarcolactic Acid,2 Hydroxypropanoic Acid,2 Hydroxypropionic Acid,D Lactic Acid,L Lactic Acid,Lactate, Ammonium

Related Publications

Vincent Thomas, and Frédéric Costes, and Michel Chatagnon, and Jean-Pierre Pouilly, and Thierry Busso
January 1989, The Japanese journal of physiology,
Vincent Thomas, and Frédéric Costes, and Michel Chatagnon, and Jean-Pierre Pouilly, and Thierry Busso
November 1994, Medicine and science in sports and exercise,
Vincent Thomas, and Frédéric Costes, and Michel Chatagnon, and Jean-Pierre Pouilly, and Thierry Busso
January 1994, European journal of applied physiology and occupational physiology,
Vincent Thomas, and Frédéric Costes, and Michel Chatagnon, and Jean-Pierre Pouilly, and Thierry Busso
January 1994, European journal of applied physiology and occupational physiology,
Vincent Thomas, and Frédéric Costes, and Michel Chatagnon, and Jean-Pierre Pouilly, and Thierry Busso
March 1989, Journal of applied physiology (Bethesda, Md. : 1985),
Vincent Thomas, and Frédéric Costes, and Michel Chatagnon, and Jean-Pierre Pouilly, and Thierry Busso
September 2001, Experimental physiology,
Vincent Thomas, and Frédéric Costes, and Michel Chatagnon, and Jean-Pierre Pouilly, and Thierry Busso
September 2011, Clinical physiology and functional imaging,
Vincent Thomas, and Frédéric Costes, and Michel Chatagnon, and Jean-Pierre Pouilly, and Thierry Busso
October 1982, Respiration physiology,
Vincent Thomas, and Frédéric Costes, and Michel Chatagnon, and Jean-Pierre Pouilly, and Thierry Busso
February 1985, International journal of sports medicine,
Vincent Thomas, and Frédéric Costes, and Michel Chatagnon, and Jean-Pierre Pouilly, and Thierry Busso
November 1996, Japanese circulation journal,
Copied contents to your clipboard!