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Fourteen mothers were treated with flecainide for fetal atrial tachycardias associated with intrauterine cardiac failure. Twelve of the 14 fetuses responded by conversion to sinus rhythm. One of the 12 fetuses subsequently died in utero. The remaining fetuses suffered no morbidity and were alive and well 3 months to 2 years after delivery. The two fetuses in whom atrial tachycardia did not convert with flecainide were successfully treated with digoxin. These results compare favourably with previous forms of antiarrhythmic treatment. After recent reports of the side effects of flecainide treatment, however, it has been advised that this drug should be confined to high risk patients and those with life threatening arrhythmias. The use of flecainide for fetal arrhythmias should be limited to patients with severe fetal hydrops and supraventricular tachycardias. It should not be the first drug of choice in atrial flutter.
L D Allan, and
S K Chita, and
G K Sharland, and
D Maxwell, and
K Priestley
February 1985,
British heart journal,
L D Allan, and
S K Chita, and
G K Sharland, and
D Maxwell, and
K Priestley
August 1987,
European heart journal,
L D Allan, and
S K Chita, and
G K Sharland, and
D Maxwell, and
K Priestley
January 2002,
Paediatric drugs,
L D Allan, and
S K Chita, and
G K Sharland, and
D Maxwell, and
K Priestley
August 1988,
The American journal of cardiology,
L D Allan, and
S K Chita, and
G K Sharland, and
D Maxwell, and
K Priestley
February 2002,
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology,
L D Allan, and
S K Chita, and
G K Sharland, and
D Maxwell, and
K Priestley
September 1988,
BMJ (Clinical research ed.),
L D Allan, and
S K Chita, and
G K Sharland, and
D Maxwell, and
K Priestley
May 1987,
Clinical cardiology,
L D Allan, and
S K Chita, and
G K Sharland, and
D Maxwell, and
K Priestley
May 2002,
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology,
L D Allan, and
S K Chita, and
G K Sharland, and
D Maxwell, and
K Priestley
February 1989,
American heart journal,
L D Allan, and
S K Chita, and
G K Sharland, and
D Maxwell, and
K Priestley
October 2015,
Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir,
