A clinicopathologic study of skin appendageal tumors. 2008

Pradeep S Nair
Department of Dermatology and Venereology, Medical College Hospital, Trivandrum- 695 011, Kerala, India. dvmchtvm@yahoo.co.in

BACKGROUND Appendageal skin tumors belong to a heterogenous group of tumors with specific histopathology. The aim of this study is to determine the pattern of appendageal tumors in skin biopsies done in our department. METHODS This is a 3-year retrospective descriptive study of all patients who were diagnosed to have skin appendageal tumors in our department, and the diagnoses were confirmed by histopathology. The tumors were classified as eccrine, hair, sebaceous, and apocrine after a detailed examination of routine hematoxylin and eosin sections. RESULTS The total number of cases in the study was 33-10 males and 23 females. Tumors with eccrine differentiation constituted the maximum, 17 cases (51.5%); followed by tumors with hair differentiation, 12 cases (36.36%); tumors with sebaceous differentiation, 2 cases (6.06%); and apocrine tumors, 2 cases (6.06%). Syringoma constituted the commonest eccrine tumor, 14 cases (42.42%); while trichoepithelioma was the commonest hair tumor, 9 cases (27.27%). The other eccrine tumors were eccrine spiradenoma, 2 cases (6.06%); and nodular hidradenoma, 1 (3.03%). The other hair tumors were pilar cyst, 2 (6.06%); and pilomatricoma, 1 (3.03%). The sebaceous tumors constituted 2 cases (6.06%) of nevus sebaceous. Syringocystadenoma papilliferum, 1 (3.03%); and cylindroma, 1 (3.03%), constituted the apocrine tumors. CONCLUSIONS Appendageal skin tumors are relatively uncommon. Histopathology is mandatory for the diagnosis. No tumor showed malignant change in this study.

UI MeSH Term Description Entries
D008297 Male Males
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D012878 Skin Neoplasms Tumors or cancer of the SKIN. Cancer of Skin,Skin Cancer,Cancer of the Skin,Neoplasms, Skin,Cancer, Skin,Cancers, Skin,Neoplasm, Skin,Skin Cancers,Skin Neoplasm
D055815 Young Adult A person between 19 and 24 years of age. Adult, Young,Adults, Young,Young Adults
D018280 Carcinoma, Skin Appendage A malignant tumor of the skin appendages, which include the hair, nails, sebaceous glands, sweat glands, and the mammary glands. (From Dorland, 27th ed) Appendage Carcinoma, Skin,Appendage Carcinomas, Skin,Carcinomas, Skin Appendage,Skin Appendage Carcinoma,Skin Appendage Carcinomas

Related Publications

Pradeep S Nair
January 1993, Clinics in plastic surgery,
Pradeep S Nair
March 1962, The Journal of investigative dermatology,
Pradeep S Nair
January 2023, Journal of cancer research and therapeutics,
Pradeep S Nair
March 1968, Surgery, gynecology & obstetrics,
Pradeep S Nair
August 1998, The journal of investigative dermatology. Symposium proceedings,
Pradeep S Nair
December 1994, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons,
Pradeep S Nair
January 2012, Journal of cytology,
Pradeep S Nair
May 1998, Pathology international,
Pradeep S Nair
September 1992, The American journal of pathology,
Copied contents to your clipboard!