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Immunoreactive levels of vasoactive intestinal peptide (IR-VIP) in the rat pineal gland were examined during the estrous cycle. IR-VIP was shown to be identical to the synthetic porcine material by its similarity in competitive binding studies, and by both gel filtration and high pressure liquid chromatography. Pineal IR-VIP decreased at early proestrus (0300 h, dark), partially as a function of the rise in serum estradiol levels. Although the functional role of VIP in the pineal remains to be clearly elucidated, these results suggest that it might be involved in the reproductive function of the female rat, and that estrogens could partially modulate its pineal concentration.
F Moujir, and
M J Lorenzo, and
R Alonso, and
C Santana, and
L Cacicedo, and
F Sanchez-Franco
January 1978,
Proceedings of the National Academy of Sciences of the United States of America,
F Moujir, and
M J Lorenzo, and
R Alonso, and
C Santana, and
L Cacicedo, and
F Sanchez-Franco
March 1982,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
F Moujir, and
M J Lorenzo, and
R Alonso, and
C Santana, and
L Cacicedo, and
F Sanchez-Franco
January 1992,
Life sciences,
F Moujir, and
M J Lorenzo, and
R Alonso, and
C Santana, and
L Cacicedo, and
F Sanchez-Franco
January 1990,
Journal of pineal research,
F Moujir, and
M J Lorenzo, and
R Alonso, and
C Santana, and
L Cacicedo, and
F Sanchez-Franco
October 2014,
Journal of biological rhythms,
F Moujir, and
M J Lorenzo, and
R Alonso, and
C Santana, and
L Cacicedo, and
F Sanchez-Franco
January 1977,
Endocrine research communications,
F Moujir, and
M J Lorenzo, and
R Alonso, and
C Santana, and
L Cacicedo, and
F Sanchez-Franco
September 1980,
Experientia,
F Moujir, and
M J Lorenzo, and
R Alonso, and
C Santana, and
L Cacicedo, and
F Sanchez-Franco
January 1987,
Biology of the cell,
F Moujir, and
M J Lorenzo, and
R Alonso, and
C Santana, and
L Cacicedo, and
F Sanchez-Franco
January 1999,
Neuro endocrinology letters,
F Moujir, and
M J Lorenzo, and
R Alonso, and
C Santana, and
L Cacicedo, and
F Sanchez-Franco
June 1997,
The Journal of endocrinology,
