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A new spectrophotometric method has been examined for the determination of the tranexamic acid (TA) by derivatization with vanillin (VAN). The molar absorptivity of TA was calculated 25,160 L x mol(-1) x cm(-1) at lambdamax 354 nm and obeyed the Beer's law within 0.5-2.5 microg x mL(-1). The color reaction was highly stable and did not show any change in absorbance up to 24 h. The method was applied for the analysis of TA from capsules, injections and tooth pastes. The amounts of TA found in capsules, injections and tooth pastes of various pharmaceutical companies were observed with 249.0-250.9 mg/capsule, 249.3-250.7 mg/injection and 0.048%-0.049% in tooth pastes with relative standard deviation (RSD) 0.2%-5.0% (n = 3).
E M A Rind, and
M G H Laghari, and
A H Memon, and
U R Mughal, and
F Almani, and
N Memon, and
M Y Khuhawar, and
M L Maheshwari
October 1990,
The Analyst,
E M A Rind, and
M G H Laghari, and
A H Memon, and
U R Mughal, and
F Almani, and
N Memon, and
M Y Khuhawar, and
M L Maheshwari
January 1984,
Talanta,
E M A Rind, and
M G H Laghari, and
A H Memon, and
U R Mughal, and
F Almani, and
N Memon, and
M Y Khuhawar, and
M L Maheshwari
September 2005,
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry,
E M A Rind, and
M G H Laghari, and
A H Memon, and
U R Mughal, and
F Almani, and
N Memon, and
M Y Khuhawar, and
M L Maheshwari
March 2007,
Chemical & pharmaceutical bulletin,
E M A Rind, and
M G H Laghari, and
A H Memon, and
U R Mughal, and
F Almani, and
N Memon, and
M Y Khuhawar, and
M L Maheshwari
April 1987,
Il Farmaco; edizione pratica,
E M A Rind, and
M G H Laghari, and
A H Memon, and
U R Mughal, and
F Almani, and
N Memon, and
M Y Khuhawar, and
M L Maheshwari
December 1998,
Talanta,
E M A Rind, and
M G H Laghari, and
A H Memon, and
U R Mughal, and
F Almani, and
N Memon, and
M Y Khuhawar, and
M L Maheshwari
July 1988,
The Analyst,
E M A Rind, and
M G H Laghari, and
A H Memon, and
U R Mughal, and
F Almani, and
N Memon, and
M Y Khuhawar, and
M L Maheshwari
January 1966,
Aptechnoe delo,
E M A Rind, and
M G H Laghari, and
A H Memon, and
U R Mughal, and
F Almani, and
N Memon, and
M Y Khuhawar, and
M L Maheshwari
June 1959,
Bollettino chimico farmaceutico,
E M A Rind, and
M G H Laghari, and
A H Memon, and
U R Mughal, and
F Almani, and
N Memon, and
M Y Khuhawar, and
M L Maheshwari
October 1976,
Ceskoslovenska farmacie,
