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The effects of a chronic treatment with ACTH and dexamethasone on the zona glomerulosa of intact rat adrenals were investigated by morphometric methods and electron microscopy. It was found that ACTH increases the volume of the zona glomerulosa, of the cells, nuclei mitochondrial compartment as well as the surface of SER and mitochondrial compartment as well as the surface of SER and mitochondrial cristae. Also noticeable was the hypertrophy of the Golgi apparatus. Opposite effects were obtained after dexamethasone treatment. These findings are interpreted as indicating that ACTH is involved in the maintenance and stimulation of the growth and steroidogenic capacity of the adrenal zona glomerulosa.
G G Nussdorfer, and
G Mazzocchi, and
C Robba, and
A S Belloni, and
P Rebuffat
March 1981,
Journal of anatomy,
G G Nussdorfer, and
G Mazzocchi, and
C Robba, and
A S Belloni, and
P Rebuffat
January 1990,
Microscopia electronica y biologia celular : organo oficial de las Sociedades Latinoamericana de Microscopia Electronica e Iberoamericana de Biologia Celular,
G G Nussdorfer, and
G Mazzocchi, and
C Robba, and
A S Belloni, and
P Rebuffat
May 1999,
Endocrine research,
G G Nussdorfer, and
G Mazzocchi, and
C Robba, and
A S Belloni, and
P Rebuffat
January 1999,
The Journal of steroid biochemistry and molecular biology,
G G Nussdorfer, and
G Mazzocchi, and
C Robba, and
A S Belloni, and
P Rebuffat
January 2002,
Histology and histopathology,
G G Nussdorfer, and
G Mazzocchi, and
C Robba, and
A S Belloni, and
P Rebuffat
January 1970,
Zeitschrift fur Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948),
G G Nussdorfer, and
G Mazzocchi, and
C Robba, and
A S Belloni, and
P Rebuffat
April 1979,
Endocrinologia japonica,
G G Nussdorfer, and
G Mazzocchi, and
C Robba, and
A S Belloni, and
P Rebuffat
October 1976,
Nihon rinsho. Japanese journal of clinical medicine,
G G Nussdorfer, and
G Mazzocchi, and
C Robba, and
A S Belloni, and
P Rebuffat
January 1987,
Acta endocrinologica,
G G Nussdorfer, and
G Mazzocchi, and
C Robba, and
A S Belloni, and
P Rebuffat
September 1984,
Proceedings of the Royal Society of London. Series B, Biological sciences,
