[The effect of lasalocid on apparent digestibility, characteristics of rumen fermentation and fattening and slaughter output of bulls]. 1990

G H Richter, and G Flachowsky
Wissenschaftsbereich Tierernährungschemie, Agrarwissenschaftliche Fakultät, Universität Leipzig.

Four digestion experiments with 5 wethers each (Feeding: artificially dried grass; 0, 15, 30 or 60 mg lasalocid per animal and day), two short time experiments (Exp. 1: 3 rumen fistulated sheep; feeding; artificially dried grass; 0, 15, 30 or 60 mg lasalocid per animal and day; exp. 2: 20 bulls; feeding; 2 kg concentrates per animal and day; wheat straw ad libitum; 0, 150 or 300 mg lasalocid per animal and day) and one individual feeding experiment (24 bulls per group; duration: 279 days, feeding: 2 kg concentrates per animal and day, corn silage and whole barley-grass silage ad libitum; 0 or 100/200 mg lasalocid per animal and day) were carried out in order to investigate the influence of the ionophore lasalocid on digestibility, figures of rumen fermentation as well as fattening and slaughtering results of bulls. Higher doses of lasalocid (30 and 60 mg per animal and day) decreased significantly digestibility of organic matter (1.8 and 2.8 units) and crude fibre (5.8 and 7.2 units). Relative acetate (22 to 120 mmoles per mol) and butyrate concentration (23 to 58 mmoles per mol) were decreased and molar propionate concentration of rumen liquid (25 to 154 mmoles per mol) was increased depending on level of lasalocid supplementation. Lasalocid did not significantly influence the dry matter intake; daily weight gain and slaughtering results were increased (4.4 and 6.1%), energy efficiency was improved (3.8%). Effects of lasalocid are similar to that of monensin. A dose of 20 to 30 mg lasalocid per kg dry matter is recommended.

UI MeSH Term Description Entries
D007832 Lasalocid Cationic ionophore antibiotic obtained from Streptomyces lasaliensis that, among other effects, dissociates the calcium fluxes in muscle fibers. It is used as a coccidiostat, especially in poultry. Avatec,Lasalocid A,Ro 2-2985,X-537A,Ro 2 2985,Ro 22985,X 537A,X537A
D008297 Male Males
D002417 Cattle Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor. Beef Cow,Bos grunniens,Bos indicus,Bos indicus Cattle,Bos taurus,Cow,Cow, Domestic,Dairy Cow,Holstein Cow,Indicine Cattle,Taurine Cattle,Taurus Cattle,Yak,Zebu,Beef Cows,Bos indicus Cattles,Cattle, Bos indicus,Cattle, Indicine,Cattle, Taurine,Cattle, Taurus,Cattles, Bos indicus,Cattles, Indicine,Cattles, Taurine,Cattles, Taurus,Cow, Beef,Cow, Dairy,Cow, Holstein,Cows,Dairy Cows,Domestic Cow,Domestic Cows,Indicine Cattles,Taurine Cattles,Taurus Cattles,Yaks,Zebus
D004043 Dietary Fiber The remnants of plant cell walls that are resistant to digestion by the alimentary enzymes of man. It comprises various polysaccharides and lignins. Fiber, Dietary,Roughage,Wheat Bran,Bran, Wheat,Brans, Wheat,Dietary Fibers,Fibers, Dietary,Roughages,Wheat Brans
D004063 Digestion The process of breakdown of food for metabolism and use by the body.
D004435 Eating The consumption of edible substances. Dietary Intake,Feed Intake,Food Intake,Macronutrient Intake,Micronutrient Intake,Nutrient Intake,Nutritional Intake,Ingestion,Dietary Intakes,Feed Intakes,Intake, Dietary,Intake, Feed,Intake, Food,Intake, Macronutrient,Intake, Micronutrient,Intake, Nutrient,Intake, Nutritional,Macronutrient Intakes,Micronutrient Intakes,Nutrient Intakes,Nutritional Intakes
D004734 Energy Metabolism The chemical reactions involved in the production and utilization of various forms of energy in cells. Bioenergetics,Energy Expenditure,Bioenergetic,Energy Expenditures,Energy Metabolisms,Expenditure, Energy,Expenditures, Energy,Metabolism, Energy,Metabolisms, Energy
D005285 Fermentation Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID. Fermentations
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012417 Rumen The first stomach of ruminants. It lies on the left side of the body, occupying the whole of the left side of the abdomen and even stretching across the median plane of the body to the right side. It is capacious, divided into an upper and a lower sac, each of which has a blind sac at its posterior extremity. The rumen is lined by mucous membrane containing no digestive glands, but mucus-secreting glands are present in large numbers. Coarse, partially chewed food is stored and churned in the rumen until the animal finds circumstances convenient for rumination. When this occurs, little balls of food are regurgitated through the esophagus into the mouth, and are subjected to a second more thorough mastication, swallowed, and passed on into other parts of the compound stomach. (From Black's Veterinary Dictionary, 17th ed) Rumens

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