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The microscopic agglutination test (MAT) is an unreliable predictor of infecting Leptospira serovar in Thailand. 2009
Lee D Smythe, and
Vanaporn Wuthiekanun, and
Wirongrong Chierakul, and
Yupin Suputtamongkol, and
Surapee Tiengrim, and
Michael F Dohnt, and
Meegan L Symonds, and
Andrew T Slack, and
Apichat Apiwattanaporn, and
Sunee Chueasuwanchai, and
Nicholas P Day, and
Sharon J Peacock
WHO/FAO/OIE Collaborating Centre for Reference and Research on Leptospirosis, Western Pacific Region, Communicable Disease Unit, Queensland Health Scientific Services, Brisbane, Australia.
A prospective study in Thailand identified 106 patients with culture-proven leptospirosis. The accuracy of the microscopic agglutination test (MAT) in predicting the infecting serovar was evaluated in 78/106 (74%) patients with a diagnostic titer. MAT correctly determined the infecting serovar in 26 cases (33%), indicating that this assay is a poor predictor of infecting serovar in our setting.
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