Biomaterial Database

Effect of HLA-DR/RFLP matching in complicated corneal transplantations. 1990

K Baggesen, and L U Lamm, and N Ehlers

Department of Ophthalmology, Arhus University Hospital, Denmark.

Fifty-one elective high-risk transplantations were matched according to HLA/DR antigens and RFLP-subtypes. The 18-month survival of the grafts was 93% in the matched group compared to 50% in a nonmatched-compatible historical control group.

UI	MeSH Term	Description	Entries
D012150	Polymorphism, Restriction Fragment Length	Variation occurring within a species in the presence or length of DNA fragment generated by a specific endonuclease at a specific site in the genome. Such variations are generated by mutations that create or abolish recognition sites for these enzymes or change the length of the fragment.	RFLP,Restriction Fragment Length Polymorphism,RFLPs,Restriction Fragment Length Polymorphisms
D006085	Graft Survival	The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.	Graft Survivals,Survival, Graft,Survivals, Graft
D006650	Histocompatibility Testing	Identification of the major histocompatibility antigens of transplant DONORS and potential recipients, usually by serological tests. Donor and recipient pairs should be of identical ABO blood group, and in addition should be matched as closely as possible for HISTOCOMPATIBILITY ANTIGENS in order to minimize the likelihood of allograft rejection. (King, Dictionary of Genetics, 4th ed)	Crossmatching, Tissue,HLA Typing,Tissue Typing,Crossmatchings, Tissue,HLA Typings,Histocompatibility Testings,Testing, Histocompatibility,Testings, Histocompatibility,Tissue Crossmatching,Tissue Crossmatchings,Tissue Typings,Typing, HLA,Typing, Tissue,Typings, HLA,Typings, Tissue
D006684	HLA-DR Antigens	A subclass of HLA-D antigens that consist of alpha and beta chains. The inheritance of HLA-DR antigens differs from that of the HLA-DQ ANTIGENS and HLA-DP ANTIGENS.	HLA-DR,Antigens, HLA-DR,HLA DR Antigens
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012189	Retrospective Studies	Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.	Retrospective Study,Studies, Retrospective,Study, Retrospective
D012307	Risk Factors	An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent.	Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor
D016039	Corneal Transplantation	Partial or total replacement of the CORNEA from one human or animal to another.	Grafting, Corneal,Keratoplasty,Keratoplasty, Lamellar,Transplantation, Corneal,Cornea Transplantation,Transplantation, Cornea,Cornea Transplantations,Corneal Grafting,Corneal Graftings,Corneal Transplantations,Graftings, Corneal,Keratoplasties,Keratoplasties, Lamellar,Lamellar Keratoplasties,Lamellar Keratoplasty,Transplantations, Cornea,Transplantations, Corneal

Related Publications

K Baggesen, and L U Lamm, and N Ehlers

Negative effect of HLA-DR matching on corneal transplant rejection.

February 1995, Transplantation proceedings,

K Baggesen, and L U Lamm, and N Ehlers

Non-HLA antigens and HLA-DR matching in corneal transplantation.

September 1996, The British journal of ophthalmology,

K Baggesen, and L U Lamm, and N Ehlers

Beneficial effect of HLA-DR matching on the survival of corneal allografts.

August 2000, Transplantation,

K Baggesen, and L U Lamm, and N Ehlers

HLA-A,B and DR matching in corneal transplantation.

October 1986, Ophthalmology,

K Baggesen, and L U Lamm, and N Ehlers

Transfusions, HLA matching and kidney transplantations.

February 1979, The New England journal of medicine,

K Baggesen, and L U Lamm, and N Ehlers

HLA-A, HLA-B and HLA-DR matching reduces the rate of corneal allograft rejection.

December 2003, Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie,

K Baggesen, and L U Lamm, and N Ehlers

[Postmortem HLA typing of corneal transplantations].

January 1987, Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft,

K Baggesen, and L U Lamm, and N Ehlers

Importance of HLA DR matching for corneal transplantation in high-risk cases.

January 1986, Cornea,

K Baggesen, and L U Lamm, and N Ehlers

Effect of HLA matching on graft survival in live donor kidney transplantations.

December 1993, Transplantation proceedings,

K Baggesen, and L U Lamm, and N Ehlers

Corneal graft survival in HLA-A- and HLA-B-matched transplantations in high-risk cases with retrospective review of HLA-DR compatibility.

January 1991, Cornea,