BIOMAT Database Logo BIOMAT Database Logo

Differential inhibition with partially purified and endogenous rabbit reticulocyte globin mRNA by 7-methylguanosine 5'-monophosphate. 1977

J M Wu, and C P Cheung, and R J Suhadolnik

UI MeSH Term Description Entries
D010142 Pactamycin Antibiotic produced by Streptomyces pactum used as an antineoplastic agent. It is also used as a tool in biochemistry because it inhibits certain steps in protein synthesis.
D011817 Rabbits A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes. Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D012156 Reticulocytes Immature ERYTHROCYTES. In humans, these are ERYTHROID CELLS that have just undergone extrusion of their CELL NUCLEUS. They still contain some organelles that gradually decrease in number as the cells mature. RIBOSOMES are last to disappear. Certain staining techniques cause components of the ribosomes to precipitate into characteristic "reticulum" (not the same as the ENDOPLASMIC RETICULUM), hence the name reticulocytes. Reticulocyte
D004151 Dipeptides Peptides composed of two amino acid units. Dipeptide
D005914 Globins A superfamily of proteins containing the globin fold which is composed of 6-8 alpha helices arranged in a characterstic HEME enclosing structure. Globin
D006150 Guanine Nucleotides Guanine Nucleotide,Guanosine Phosphates,Nucleotide, Guanine,Nucleotides, Guanine,Phosphates, Guanosine
D006157 Guanosine Monophosphate A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. 5'-Guanylic Acid,Guanosine 5'-Monophosphate,5'-GMP,Guanylic Acid,5' Guanylic Acid,5'-Monophosphate, Guanosine,Acid, 5'-Guanylic,Acid, Guanylic,Guanosine 5' Monophosphate,Monophosphate, Guanosine
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012333 RNA, Messenger RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm. Messenger RNA,Messenger RNA, Polyadenylated,Poly(A) Tail,Poly(A)+ RNA,Poly(A)+ mRNA,RNA, Messenger, Polyadenylated,RNA, Polyadenylated,mRNA,mRNA, Non-Polyadenylated,mRNA, Polyadenylated,Non-Polyadenylated mRNA,Poly(A) RNA,Polyadenylated mRNA,Non Polyadenylated mRNA,Polyadenylated Messenger RNA,Polyadenylated RNA,RNA, Polyadenylated Messenger,mRNA, Non Polyadenylated
D013329 Structure-Activity Relationship The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups. Relationship, Structure-Activity,Relationships, Structure-Activity,Structure Activity Relationship,Structure-Activity Relationships

Related Publications

J M Wu, and C P Cheung, and R J Suhadolnik
7-Methylguanosine-dependent inhibition of globin mRNA translation by methylglyoxal.
October 1979, The Journal of biological chemistry,
J M Wu, and C P Cheung, and R J Suhadolnik
Effect of 7-methylguanosine-5'-phosphate on rabbit globin synthesis.
December 1976, FEBS letters,
J M Wu, and C P Cheung, and R J Suhadolnik
Inhibition of initiation of protein synthesis by 7-methylguanosine-5'-monophosphate.
January 1976, Proceedings of the National Academy of Sciences of the United States of America,
J M Wu, and C P Cheung, and R J Suhadolnik
Inhibition of ovalbumin mRNA translation by 7-methylguanosine-5'-phosphate.
October 1976, Biochemical and biophysical research communications,
J M Wu, and C P Cheung, and R J Suhadolnik
Inhibition of HeLa cell messenger RNA translation by 7-methylguanosine 5'-monophosphate.
September 1976, The Journal of biological chemistry,
J M Wu, and C P Cheung, and R J Suhadolnik
Inhibition of globin synthesis by rabbit reticulocyte rRNAs.
April 1978, Journal of biochemistry,
J M Wu, and C P Cheung, and R J Suhadolnik
Inhibition of noncapped mRNA translation by the cap analogue, 7-methylguanosine-5'-phosphate.
May 1978, Biochemical and biophysical research communications,
J M Wu, and C P Cheung, and R J Suhadolnik
Globin mRNA from rabbit reticulocyte membrane-bound ribosomes.
January 1975, Biochimica et biophysica acta,
J M Wu, and C P Cheung, and R J Suhadolnik
Base stacking of simple mRNA cap analogues. Association of 7,9-dimethylguanine, 7-methylguanosine and 7-methylguanosine 5'-monophosphate with indole and purine derivatives in aqueous solution.
July 1989, Biophysical chemistry,
J M Wu, and C P Cheung, and R J Suhadolnik
Requirement for 7-methylguanosine in translation of globin mRNA in vivo.
September 1978, Nucleic acids research,
Copied contents to your clipboard!