Low potassium-type but not high potassium-type sheep red blood cells show passive K+ transport induced by low ionic strength. 1991

A Erdmann, and I Bernhardt, and S J Pittman, and J C Ellory
Department of Biophysics, Humboldt University, Berlin, G.D.R.

Low potassium-type (LK) sheep red blood cells show a significant increase of the residual (i.e., ouabain-insensitive) K+ influx when the ionic strength of the solution is decreased. This effect is absent from high potassium-type (HK) sheep red blood cells. The KCl cotransport system is not involved since three different manoeuvres to suppress the KCl cotransport (replacement of Cl- by NO3-, volume-decrease, inhibition by anti-L1 antibodies) have no effect on the low ionic strength-stimulated K+ influx.

UI MeSH Term Description Entries
D009994 Osmolar Concentration The concentration of osmotically active particles in solution expressed in terms of osmoles of solute per liter of solution. Osmolality is expressed in terms of osmoles of solute per kilogram of solvent. Ionic Strength,Osmolality,Osmolarity,Concentration, Osmolar,Concentrations, Osmolar,Ionic Strengths,Osmolalities,Osmolar Concentrations,Osmolarities,Strength, Ionic,Strengths, Ionic
D010042 Ouabain A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE. Acocantherin,G-Strophanthin,Acolongifloroside K,G Strophanthin
D011188 Potassium An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
D002352 Carrier Proteins Proteins that bind or transport specific substances in the blood, within the cell, or across cell membranes. Binding Proteins,Carrier Protein,Transport Protein,Transport Proteins,Binding Protein,Protein, Carrier,Proteins, Carrier
D002712 Chlorides Inorganic compounds derived from hydrochloric acid that contain the Cl- ion. Chloride,Chloride Ion Level,Ion Level, Chloride,Level, Chloride Ion
D004911 Erythrocyte Volume Volume of circulating ERYTHROCYTES . It is usually measured by RADIOISOTOPE DILUTION TECHNIQUE. Red Cell Mass,Erythrocyte Volumes,Mass, Red Cell,Masses, Red Cell,Red Cell Masses,Volume, Erythrocyte,Volumes, Erythrocyte
D004912 Erythrocytes Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN. Blood Cells, Red,Blood Corpuscles, Red,Red Blood Cells,Red Blood Corpuscles,Blood Cell, Red,Blood Corpuscle, Red,Erythrocyte,Red Blood Cell,Red Blood Corpuscle
D000096922 K Cl- Cotransporters A subclass of symporters that specifically transport POTASSIUM and CHLORIDE ions across cellular membranes. Potassium chloride cotransporters play roles in regulating cell volume and intracellular chloride concentration. Electroneutral Potassium-Chloride Co-transporter 3,Electroneutral Potassium-Chloride Cotransporter 3,K Cl- Co-transporters,K(+), Cl(-)-Co-transporters,K(+), Cl(-)-Cotransporters,K-Cl Co-transporter,K-Cl Co-transporter 3,K-Cl Cotransporter,K-Cl Cotransporter 3,KCC2 Co-transporter,KCC2 Cotransporter,KCC3 Co-transporter,KCC3 Cotransporter,KCC4 Co-transporter,KCC4 Cotransporter,Potassium-Chloride Co-transporter 2,Potassium-Chloride Co-transporter 4,Potassium-Chloride Co-transporters,Potassium-Chloride Cotransporter 2,Potassium-Chloride Cotransporter 4,Potassium-Chloride Cotransporters,Potassium-Chloride Symporters,SLC12A5 Protein,SLC12A6 Protein,SLC12A7 Protein,Solute Carrier Family 12 Member 5,Solute Carrier Family 12 Member 6,Solute carrier family 12 member 7,Cl- Co-transporters, K,Co-transporter 2, Potassium-Chloride,Co-transporter 3, K-Cl,Co-transporter 4, Potassium-Chloride,Co-transporter, K-Cl,Co-transporter, KCC2,Co-transporter, KCC3,Co-transporter, KCC4,Co-transporters, K Cl-,Co-transporters, Potassium-Chloride,Cotransporter, K-Cl,Cotransporter, KCC2,Cotransporter, KCC3,Cotransporter, KCC4,Cotransporters, K Cl-,Cotransporters, Potassium-Chloride,Electroneutral Potassium Chloride Co transporter 3,Electroneutral Potassium Chloride Cotransporter 3,K Cl Co transporter,K Cl Co transporter 3,K Cl Co transporters,K Cl Cotransporter,K Cl Cotransporter 3,K Cl Cotransporters,KCC2 Co transporter,KCC3 Co transporter,KCC4 Co transporter,Potassium Chloride Co transporter 2,Potassium Chloride Co transporter 4,Potassium Chloride Co transporters,Potassium Chloride Cotransporter 2,Potassium Chloride Cotransporter 4,Potassium Chloride Cotransporters,Potassium Chloride Symporters,Protein, SLC12A5,Protein, SLC12A6,Protein, SLC12A7
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001692 Biological Transport The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments. Transport, Biological,Biologic Transport,Transport, Biologic

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