BIOMAT Database Logo BIOMAT Database Logo

A comparison of retinal prosthesis electrode array substrate materials. 2009

James D Weiland, and Mark S Humayun, and Helmut Eckhardt, and Stefan Ufer, and Lucien Laude, and Brooke Basinger, and Yu-Chong Tai
Doheny Eye Institute, Los Angeles, California, USA.

Simulations of artificial vision suggest that 1000 electrodes may be required to restore vision to individuals with diseases of the outer retina. In order to achieve such an implant, new technology is needed, since the state-of-the-art implantable neural stimulator has at most 22 contacts with neural tissue. A critical component of this system is the multi-channel, stimulating electrode array. This array must meet very challenging, competing requirements for manufacturing, integration, surgical handling, and biocompatibility. Our lab has evaluated 3 polymers as retinal prosthesis substrates: polyimide, parylene, and silicone.

UI MeSH Term Description Entries
D007834 Lasers An optical source that emits photons in a coherent beam. Light Amplification by Stimulated Emission of Radiation (LASER) is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the infrared, visible, ultraviolet, or X-ray regions of the spectrum. Masers,Continuous Wave Lasers,Pulsed Lasers,Q-Switched Lasers,Continuous Wave Laser,Laser,Laser, Continuous Wave,Laser, Pulsed,Laser, Q-Switched,Lasers, Continuous Wave,Lasers, Pulsed,Lasers, Q-Switched,Maser,Pulsed Laser,Q Switched Lasers,Q-Switched Laser
D011108 Polymers Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS). Polymer
D011474 Prosthesis Design The plan and delineation of prostheses in general or a specific prosthesis. Design, Prosthesis,Designs, Prosthesis,Prosthesis Designs
D012160 Retina The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent. Ora Serrata
D012164 Retinal Diseases Diseases involving the RETINA. Disease, Retinal,Diseases, Retinal,Retinal Disease
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D004558 Electric Stimulation Use of electric potential or currents to elicit biological responses. Stimulation, Electric,Electrical Stimulation,Electric Stimulations,Electrical Stimulations,Stimulation, Electrical,Stimulations, Electric,Stimulations, Electrical
D004566 Electrodes Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum. Anode,Anode Materials,Cathode,Cathode Materials,Anode Material,Anodes,Cathode Material,Cathodes,Electrode,Material, Anode,Material, Cathode
D004567 Electrodes, Implanted Surgically placed electric conductors through which ELECTRIC STIMULATION is delivered to or electrical activity is recorded from a specific point inside the body. Implantable Electrodes,Implantable Stimulation Electrodes,Implanted Electrodes,Implanted Stimulation Electrodes,Electrode, Implantable,Electrode, Implantable Stimulation,Electrode, Implanted,Electrode, Implanted Stimulation,Electrodes, Implantable,Electrodes, Implantable Stimulation,Electrodes, Implanted Stimulation,Implantable Electrode,Implantable Stimulation Electrode,Implanted Electrode,Implanted Stimulation Electrode,Stimulation Electrode, Implantable,Stimulation Electrode, Implanted,Stimulation Electrodes, Implantable,Stimulation Electrodes, Implanted
D004867 Equipment Design Methods and patterns of fabricating machines and related hardware. Design, Equipment,Device Design,Medical Device Design,Design, Medical Device,Designs, Medical Device,Device Design, Medical,Device Designs, Medical,Medical Device Designs,Design, Device,Designs, Device,Designs, Equipment,Device Designs,Equipment Designs

Related Publications

James D Weiland, and Mark S Humayun, and Helmut Eckhardt, and Stefan Ufer, and Lucien Laude, and Brooke Basinger, and Yu-Chong Tai
Comparison of electrode materials for the use of retinal prosthesis.
January 2011, Bio-medical materials and engineering,
James D Weiland, and Mark S Humayun, and Helmut Eckhardt, and Stefan Ufer, and Lucien Laude, and Brooke Basinger, and Yu-Chong Tai
Diamond penetrating electrode array for epi-retinal prosthesis.
January 2010, Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference,
James D Weiland, and Mark S Humayun, and Helmut Eckhardt, and Stefan Ufer, and Lucien Laude, and Brooke Basinger, and Yu-Chong Tai
Flexible microelectrode array for retinal prosthesis.
July 2017, Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference,
James D Weiland, and Mark S Humayun, and Helmut Eckhardt, and Stefan Ufer, and Lucien Laude, and Brooke Basinger, and Yu-Chong Tai
The subretinal microphotodiode array retinal prosthesis.
January 1998, Ophthalmic research,
James D Weiland, and Mark S Humayun, and Helmut Eckhardt, and Stefan Ufer, and Lucien Laude, and Brooke Basinger, and Yu-Chong Tai
The subretinal microphotodiode array retinal prosthesis II.
January 1999, Ophthalmic research,
James D Weiland, and Mark S Humayun, and Helmut Eckhardt, and Stefan Ufer, and Lucien Laude, and Brooke Basinger, and Yu-Chong Tai
Investigation of a new electrode array technology for a central auditory prosthesis.
January 2013, PloS one,
James D Weiland, and Mark S Humayun, and Helmut Eckhardt, and Stefan Ufer, and Lucien Laude, and Brooke Basinger, and Yu-Chong Tai
The development of a multichannel electrode array for retinal prostheses.
January 2006, Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs,
James D Weiland, and Mark S Humayun, and Helmut Eckhardt, and Stefan Ufer, and Lucien Laude, and Brooke Basinger, and Yu-Chong Tai
Effect of the electrode array-retina gap distance on visual function in patients with the Argus II retinal prosthesis.
September 2020, BMC ophthalmology,
James D Weiland, and Mark S Humayun, and Helmut Eckhardt, and Stefan Ufer, and Lucien Laude, and Brooke Basinger, and Yu-Chong Tai
An all-diamond, hermetic electrical feedthrough array for a retinal prosthesis.
January 2014, Biomaterials,
James D Weiland, and Mark S Humayun, and Helmut Eckhardt, and Stefan Ufer, and Lucien Laude, and Brooke Basinger, and Yu-Chong Tai
[The research progress on microelectrode array (MEA) of retinal prosthesis].
September 2010, Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation,
Copied contents to your clipboard!