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Autophagy: where next? 2010

David C Rubinsztein
Department of Medical Genetics, University of Cambridge, UK. dcr1000@hermes.cam.ac.uk

UI MeSH Term Description Entries
D003585 Cell Biology The study of the structure, behavior, growth, reproduction, and pathology of cells; and the function and chemistry of cellular components. Cellular Biology,Biologies, Cell,Biologies, Cellular,Biology, Cell,Biology, Cellular,Cell Biologies,Cellular Biologies
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001343 Autophagy The segregation and degradation of various cytoplasmic constituents via engulfment by MULTIVESICULAR BODIES; VACUOLES; or AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer. Autophagocytosis,ER-Phagy,Lipophagy,Nucleophagy,Reticulophagy,Ribophagy,Autophagy, Cellular,Cellular Autophagy,ER Phagy

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