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Breathing pattern in response to maximal exercise was examined in four subjects during a 7-day acclimatisation to a simulated altitude of 4247 m (barometric pressure, PB = 59.5 kPa). Graded exercise tests to exhaustion were performed during normoxia (day 0), and on days 2 and 7 of hypoxia, respectively. Ventilation was significantly augmented in the hypoxic environment, as were both the mean inspiratory flow (VT/TI) and inspiratory duty cycle (TI/TTOT) components of it. VI/TI was increased due to a significant increase in tidal volume (VT) and a corresponding decrease in inspiratory time duration (TI). Throughout a range of exercise ventilation, TI/TTOT was increased due to an apparently greater decrease in expiratory time duration (TE) with respect to TI. In all cases, the relation between VT and TI displayed a typical range 2 behaviour, with evidence of a range 3 occurring at very high ventilatory rates. There was essentially no difference observed in the VT-TI relation during exercise between the normoxic and hypoxic conditions. No significant changes were observed in the breathing pattern in response to exercise within the exposure period (from day 2 to day 7), although there was a discernible tendency to a higher stage 3 plateau by day 7 of altitude exposure.
I B Mekjavic, and
C Moric, and
S V Goldberg, and
J B Morrison, and
M L Walsh, and
E W Banister, and
R B Schoene
October 1981,
Minerva medica,
I B Mekjavic, and
C Moric, and
S V Goldberg, and
J B Morrison, and
M L Walsh, and
E W Banister, and
R B Schoene
December 2001,
International journal of cardiology,
I B Mekjavic, and
C Moric, and
S V Goldberg, and
J B Morrison, and
M L Walsh, and
E W Banister, and
R B Schoene
March 1981,
Pharmacological research communications,
I B Mekjavic, and
C Moric, and
S V Goldberg, and
J B Morrison, and
M L Walsh, and
E W Banister, and
R B Schoene
January 1987,
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas,
I B Mekjavic, and
C Moric, and
S V Goldberg, and
J B Morrison, and
M L Walsh, and
E W Banister, and
R B Schoene
January 1987,
European journal of applied physiology and occupational physiology,
I B Mekjavic, and
C Moric, and
S V Goldberg, and
J B Morrison, and
M L Walsh, and
E W Banister, and
R B Schoene
January 1984,
Acta physiologica Scandinavica,
I B Mekjavic, and
C Moric, and
S V Goldberg, and
J B Morrison, and
M L Walsh, and
E W Banister, and
R B Schoene
February 1989,
Respiration physiology,
I B Mekjavic, and
C Moric, and
S V Goldberg, and
J B Morrison, and
M L Walsh, and
E W Banister, and
R B Schoene
January 1988,
The European respiratory journal,
I B Mekjavic, and
C Moric, and
S V Goldberg, and
J B Morrison, and
M L Walsh, and
E W Banister, and
R B Schoene
November 2008,
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas,
I B Mekjavic, and
C Moric, and
S V Goldberg, and
J B Morrison, and
M L Walsh, and
E W Banister, and
R B Schoene
July 1987,
Journal of applied physiology (Bethesda, Md. : 1985),
