-transparent.png){kind=logo}
The mutagenic and carcinogenic effects of parathion-methyl were examined by bacterial reverse mutation assay and a long-term experiment with wistar rats. The potential mutagenic effect of parathion-methyl in Salmonella typhimurium TA100 bacterial cells was observed without rat liver S9 metabolic activation. Parathion-methyl was further investigated for pathological changes in rat pancreas and liver. The long-term rat experiments showed that parathion-methyl exposure for 3 months can cause pathological changes in rat pancreases acinar cells and pancreatic hepatocytes. Atypical acinar cell focuses (AACF) were determined in the liver and pancreas of the rats. The results from short-term Ames test and long-term rat experiments suggested that parathion-methyl would be potential carcinogenic.
M Nisa Unaldi Coral, and
Sonay Ucman, and
Hasan Yildiz, and
Haydar Oztas, and
Semih Dalkilic
April 1990,
JPMA. The Journal of the Pakistan Medical Association,
M Nisa Unaldi Coral, and
Sonay Ucman, and
Hasan Yildiz, and
Haydar Oztas, and
Semih Dalkilic
November 1990,
JPMA. The Journal of the Pakistan Medical Association,
M Nisa Unaldi Coral, and
Sonay Ucman, and
Hasan Yildiz, and
Haydar Oztas, and
Semih Dalkilic
January 1985,
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes,
M Nisa Unaldi Coral, and
Sonay Ucman, and
Hasan Yildiz, and
Haydar Oztas, and
Semih Dalkilic
January 2003,
Journal of toxicology and environmental health. Part B, Critical reviews,
M Nisa Unaldi Coral, and
Sonay Ucman, and
Hasan Yildiz, and
Haydar Oztas, and
Semih Dalkilic
January 1983,
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans,
M Nisa Unaldi Coral, and
Sonay Ucman, and
Hasan Yildiz, and
Haydar Oztas, and
Semih Dalkilic
December 1996,
Bulletin of environmental contamination and toxicology,
M Nisa Unaldi Coral, and
Sonay Ucman, and
Hasan Yildiz, and
Haydar Oztas, and
Semih Dalkilic
February 1968,
Journal of economic entomology,
M Nisa Unaldi Coral, and
Sonay Ucman, and
Hasan Yildiz, and
Haydar Oztas, and
Semih Dalkilic
March 1979,
Bulletin of environmental contamination and toxicology,
M Nisa Unaldi Coral, and
Sonay Ucman, and
Hasan Yildiz, and
Haydar Oztas, and
Semih Dalkilic
May 2005,
Environmental toxicology and pharmacology,
M Nisa Unaldi Coral, and
Sonay Ucman, and
Hasan Yildiz, and
Haydar Oztas, and
Semih Dalkilic
February 2007,
Huan jing ke xue= Huanjing kexue,
