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Synthesis of the 6'-iso analogues of neplanocin A and 5'-homoneplanocin A. 2009

Wei Ye, and Mingzhu He, and Stewart W Schneller
Department of Chemistry and Biochemistry, Auburn University, Auburn, AL 36849-5312.

An efficient synthesis of 6'-isoneplanocin A and 6-isohomoneplanocin A is reported. The key steps in the synthesis include an enyne metathesis and a regioselective oxidation.

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