-transparent.png){kind=logo}
OBJECTIVE To determine the effect of early excision and closure of burns on postburn hypermetabolism, measured as oxygen consumption (VO2). METHODS Twelve patients with deep burns of 30% to 50% of total body surface underwent sequential excisions and wound coverage, beginning 1 to 3 days after burn. The majority of the deep burn was removed by day 7, but with the addition of a donor site area of 20% to 25% of total body surface. RESULTS No decrease in VO2 was noted in relation to the percent removal of burn tissue. In addition, a transient further increase in VO2 was noted early after excision, especially with surgical procedures performed after 5 days. This response could not be attributed to wound manipulation-induced bacteremias. CONCLUSIONS We conclude that early surgical excision and closure of burns in excess of 30% to 50% of total body surface do not decrease postburn hypermetabolism in proportion to the area closed. It is possible that remaining open wounds in the form of donor sites and nonexcised burn are sufficient to perpetuate the hypermetabolic process, once established.
R H Demling, and
E Frye, and
T Read
November 1987,
Surgery,
R H Demling, and
E Frye, and
T Read
November 1988,
Surgery,
R H Demling, and
E Frye, and
T Read
January 1986,
The Journal of burn care & rehabilitation,
R H Demling, and
E Frye, and
T Read
June 1985,
Annals of plastic surgery,
R H Demling, and
E Frye, and
T Read
December 1988,
Archives of surgery (Chicago, Ill. : 1960),
R H Demling, and
E Frye, and
T Read
July 1990,
Surgery,
R H Demling, and
E Frye, and
T Read
January 2000,
Acta chirurgiae plasticae,
R H Demling, and
E Frye, and
T Read
April 2003,
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns,
R H Demling, and
E Frye, and
T Read
September 1998,
Burns : journal of the International Society for Burn Injuries,
R H Demling, and
E Frye, and
T Read
June 1997,
The Journal of trauma,
