-transparent.png){kind=logo}
The stalk cell differentiation inducing factor (DIF) has the properties required of a morphogen responsible for pattern regulation during the pseudoplasmodial stage of Dictyostelium development. It induces prestalk cell formation and inhibits prespore cell formation, but there is as yet no strong evidence for a morphogenetic gradient of DIF. We have measured DIF accumulation by monolayers of isolated prestalk and prespore cells in an attempt to provide evidence for such a gradient. DIF is accumulated in the largest quantities by a subpopulation of prestalk cells that specifically express the DIF-inducible genes pDd56 and pDd26. Since it has been shown recently that cells that express pDd56 are localized in the central core of the prestalk cell region of the pseudoplasmodia, our current results suggest a morphogenetic gradient generated by this region.
L Kwong, and
Y J Xie, and
J Daniel, and
S M Robbins, and
G Weeks
September 1988,
Development (Cambridge, England),
L Kwong, and
Y J Xie, and
J Daniel, and
S M Robbins, and
G Weeks
December 1999,
Seminars in cell & developmental biology,
L Kwong, and
Y J Xie, and
J Daniel, and
S M Robbins, and
G Weeks
April 1987,
Cell,
L Kwong, and
Y J Xie, and
J Daniel, and
S M Robbins, and
G Weeks
January 1985,
Development, growth & differentiation,
L Kwong, and
Y J Xie, and
J Daniel, and
S M Robbins, and
G Weeks
May 1985,
Developmental biology,
L Kwong, and
Y J Xie, and
J Daniel, and
S M Robbins, and
G Weeks
January 1995,
Developmental biology,
L Kwong, and
Y J Xie, and
J Daniel, and
S M Robbins, and
G Weeks
March 1991,
Development (Cambridge, England),
L Kwong, and
Y J Xie, and
J Daniel, and
S M Robbins, and
G Weeks
June 1988,
Developmental biology,
L Kwong, and
Y J Xie, and
J Daniel, and
S M Robbins, and
G Weeks
March 2010,
Developmental biology,
L Kwong, and
Y J Xie, and
J Daniel, and
S M Robbins, and
G Weeks
December 1981,
Differentiation; research in biological diversity,
