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myo-Inositol deficiency in rats produced an overaccumulation of triacylglycerols in the liver due to stimulated lipolysis in the adipose tissue (Hayashi, E., Maeda, T. and Tomita, T. (1974) Biochim. Biophys. Acta 360, 134--155). The mechanism of the enhancement in lipolysis has now been investigated. The lipolytic response to adrenalin, corticotropin and insulin of the epididymal adipose tissue did not change due to the deficiency, but hormone-sensitive lipase activity, plasma adrenalin level and blood pressure were higher in the deficient rats. Adrenalectomy had no influence, but administration of sympathetic nervous blockers (reserpine, hexamethonium and bupranolol) inhibited the liver lipid deposition and an increase of serum free fatty acids in the deficient rats. These results indicate that the enhancement in lipolysis is mediated by an excitation of sympathetic nerve terminals innervating in the adipose tissues.
E Hayashi, and
T Maeda, and
R Hasegawa, and
T Tomita
February 1987,
Biochimica et biophysica acta,
E Hayashi, and
T Maeda, and
R Hasegawa, and
T Tomita
June 1979,
The Biochemical journal,
E Hayashi, and
T Maeda, and
R Hasegawa, and
T Tomita
August 1984,
European journal of biochemistry,
E Hayashi, and
T Maeda, and
R Hasegawa, and
T Tomita
May 1978,
Biochimica et biophysica acta,
E Hayashi, and
T Maeda, and
R Hasegawa, and
T Tomita
March 1965,
The Journal of vitaminology,
E Hayashi, and
T Maeda, and
R Hasegawa, and
T Tomita
September 1967,
Ceskoslovenska gastroenterologie a vyziva,
E Hayashi, and
T Maeda, and
R Hasegawa, and
T Tomita
September 1961,
The Journal of biological chemistry,
E Hayashi, and
T Maeda, and
R Hasegawa, and
T Tomita
October 1969,
Annals of the New York Academy of Sciences,
E Hayashi, and
T Maeda, and
R Hasegawa, and
T Tomita
October 1969,
Annals of the New York Academy of Sciences,
E Hayashi, and
T Maeda, and
R Hasegawa, and
T Tomita
January 1990,
Nephron,
