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Exposure of human skin to short wavelength ultraviolet (U.V.) leads to increased concentrations of arachidonic acid and prostaglandins E2 and F2, but their role is uncertain. Although the levels of prostaglandins rise as erythema develops the correlation between intensity of erythema and prostaglandin activity is incomplete. There is mounting evidence that prostaglandins may regulate epidermal cell growth and differentiation through a cyclic-AMP dependent mechanism. The possibility therefore arises that prostaglandins, released in response to U. V. exposure, reduce proliferative activity in the exposed epidermis. This can be expected, in turn, to result in protection of skin from the mutagenic action of U. V. irradiation.
M W Greaves, and
C N Hensby, and
A K Black, and
N A Plummer, and
N Fincham, and
A P Warin, and
R Camp
January 2021,
Journal of photochemistry and photobiology. B, Biology,
M W Greaves, and
C N Hensby, and
A K Black, and
N A Plummer, and
N Fincham, and
A P Warin, and
R Camp
January 1981,
Biofizika,
M W Greaves, and
C N Hensby, and
A K Black, and
N A Plummer, and
N Fincham, and
A P Warin, and
R Camp
September 1985,
Archives of dermatology,
M W Greaves, and
C N Hensby, and
A K Black, and
N A Plummer, and
N Fincham, and
A P Warin, and
R Camp
December 1979,
Archives of dermatology,
M W Greaves, and
C N Hensby, and
A K Black, and
N A Plummer, and
N Fincham, and
A P Warin, and
R Camp
July 1995,
Physical review. B, Condensed matter,
M W Greaves, and
C N Hensby, and
A K Black, and
N A Plummer, and
N Fincham, and
A P Warin, and
R Camp
June 1974,
Nature,
M W Greaves, and
C N Hensby, and
A K Black, and
N A Plummer, and
N Fincham, and
A P Warin, and
R Camp
March 1948,
Current science,
M W Greaves, and
C N Hensby, and
A K Black, and
N A Plummer, and
N Fincham, and
A P Warin, and
R Camp
January 1976,
Journal of molecular biology,
M W Greaves, and
C N Hensby, and
A K Black, and
N A Plummer, and
N Fincham, and
A P Warin, and
R Camp
March 1956,
The American journal of physiology,
M W Greaves, and
C N Hensby, and
A K Black, and
N A Plummer, and
N Fincham, and
A P Warin, and
R Camp
September 1966,
The American journal of pathology,
