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A field strain (87-8363) of bovid herpesvirus-4 (BHV-4) isolated from an aborted bovine fetus was used to inoculate pregnant rabbits. Eleven rabbits in midgestation were alloted to 4 groups consisting of 3 infected groups and 1 control group. Rabbits were inoculated with BHV-4 or mock-infected cell culture preparations via IV, intravaginal, and intrauterine routes. Mild vulvovaginitis and endometritis were observed after intravaginal and IV inoculation of BHV-4, whereas intrauterine inoculation of BHV-4 resulted in abortion of hemorrhagic fetuses and nonsuppurative endometritis. Virus was successfully isolated from organ explants of fetal tissues. Rabbits seroconverted 1 week after infection as detected by results of an indirect immunofluorescence assay.
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D D Caywood, and
R E Werdin, and
S M Goyal
January 1987,
Comparative immunology, microbiology and infectious diseases,
K Naeem, and
D D Caywood, and
R E Werdin, and
S M Goyal
January 1987,
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K Naeem, and
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K Naeem, and
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K Naeem, and
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K Naeem, and
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S M Goyal
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K Naeem, and
D D Caywood, and
R E Werdin, and
S M Goyal
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Comparative immunology, microbiology and infectious diseases,
K Naeem, and
D D Caywood, and
R E Werdin, and
S M Goyal
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K Naeem, and
D D Caywood, and
R E Werdin, and
S M Goyal
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Veterinary microbiology,
K Naeem, and
D D Caywood, and
R E Werdin, and
S M Goyal
September 1987,
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B,
