Biomaterial Database

[Diversity of etiological agent associated with aseptic meningitis--a survey on an epidemic in Tajimi City, Gifu Prefecture in 1984]. 1990

C Miwa, and Y Watanabe

Gifu Prefectural Institute of Public Health.

During the period from May to September in 1984, an epidemic of aseptic meningitis occurred in Tajimi city, Gifu prefecture. Virological and serological investigations were performed. Cases involved ranged from 0 to 12 years of age, and 83.1% of them were under 7 years of age. Four types of enteroviruses were isolated from 38 to 59 cases (64.4%), and virus type isolated were coxsackie B1 (15 cases), B4 (2 cases), B5 (4 cases), echovirus 16 (14 cases), a mixture of coxsackie-virus B4 and echovirus 16 (2 cases) and an unidentified strain (one cases). Virus types isolated from cerebrospinal fluid were coxsackievirus B1 and B5. In the serological studies of 47 paired sera of patients, a significant rise in titer against 4 virus types isolated was 29.8% with coxsackievirus B1, 12.8% with coxasackievirus B4, 17.0% with coxsackievirus B5, and 34.0% with echovirus 16. In relation between virus type isolated and a significant rise in titer of neutralizing antibody, almost all of the patients' sera (80.0%) exhibited a significant rise in titer of neutralizing antibody against one isolated virus type, but some patient's sera (20.0%) exhibited a significant rise against two or more of the viruses.

UI	MeSH Term	Description	Entries
D007223	Infant	A child between 1 and 23 months of age.	Infants
D007564	Japan	A country in eastern Asia, island chain between the North Pacific Ocean and the Sea of Japan, east of the Korean Peninsula. The capital is Tokyo.	Bonin Islands
D008297	Male		Males
D008587	Meningitis, Viral	Viral infections of the leptomeninges and subarachnoid space. TOGAVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; RUBELLA; BUNYAVIRIDAE INFECTIONS; ORBIVIRUS infections; PICORNAVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RHABDOVIRIDAE INFECTIONS; ARENAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; JC VIRUS infections; and RETROVIRIDAE INFECTIONS may cause this form of meningitis. Clinical manifestations include fever, headache, neck pain, vomiting, PHOTOPHOBIA, and signs of meningeal irritation. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3)	Viral Meningitis,Meningitides, Viral,Viral Meningitides
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D003384	Coxsackievirus Infections	A heterogeneous group of infections produced by coxsackieviruses, including HERPANGINA, aseptic meningitis (MENINGITIS, ASEPTIC), a common-cold-like syndrome, a non-paralytic poliomyelitis-like syndrome, epidemic pleurodynia (PLEURODYNIA, EPIDEMIC) and a serious MYOCARDITIS.	Coxsackie Virus Infections,Infections, Coxsackie Virus,Infections, Coxsackievirus,Coxsackie Virus Infection,Coxsackievirus Infection
D004196	Disease Outbreaks	Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.	Outbreaks,Infectious Disease Outbreaks,Disease Outbreak,Disease Outbreak, Infectious,Disease Outbreaks, Infectious,Infectious Disease Outbreak,Outbreak, Disease,Outbreak, Infectious Disease,Outbreaks, Disease,Outbreaks, Infectious Disease
D004457	Echovirus Infections	Infectious disease processes, including meningitis, diarrhea, and respiratory disorders, caused by echoviruses.	Echo Virus Infections,Infections, Echo Virus,Infections, Echovirus,Echo Virus Infection,Echovirus Infection,Infection, Echo Virus,Infection, Echovirus
D005260	Female		Females