[Epidemic of aseptic meningitis with echovirus type 30 in Gifu Prefecture]. 1993

C Miwa, and S Sawatari
Gifu Prefectural Health and Environment Research Center.

During July to December in 1991, an epidemic of aseptic meningitis occurred in Gifu Prefecture in children. Epidemiological, virological and serological investigations were performed. The results are as follows: 1) Cases involved ranged from 0 to 13 years of age, and 75.9% of them were in the 3 to 7 year of age group. 2) Three types of enteroviruses were isolated from 83 of 133 cases (62.4%), and the echovirus type 30 was recovered from 71 cases (85.5%). 3) In 1991 with the cross neutralizing test between the prototype and isolated strains of echovirus type 30, a remarkable antigenic variation could not be found. 4) In serological studies, the positive rates of neutralizing antibodies to echovirus type 30 in infant sera aged 0-9 years in 1992-1993, was 51.9% with the prototype strain, but 34.0% with an isolated strain in 1991.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007564 Japan A country in eastern Asia, island chain between the North Pacific Ocean and the Sea of Japan, east of the Korean Peninsula. The capital is Tokyo. Bonin Islands
D008582 Meningitis, Aseptic A syndrome characterized by headache, neck stiffness, low grade fever, and CSF lymphocytic pleocytosis in the absence of an acute bacterial pathogen. Viral meningitis is the most frequent cause although MYCOPLASMA INFECTIONS; RICKETTSIA INFECTIONS; diagnostic or therapeutic procedures; NEOPLASTIC PROCESSES; septic perimeningeal foci; and other conditions may result in this syndrome. (From Adams et al., Principles of Neurology, 6th ed, p745) Aseptic Meningitis
D008587 Meningitis, Viral Viral infections of the leptomeninges and subarachnoid space. TOGAVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; RUBELLA; BUNYAVIRIDAE INFECTIONS; ORBIVIRUS infections; PICORNAVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RHABDOVIRIDAE INFECTIONS; ARENAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; JC VIRUS infections; and RETROVIRIDAE INFECTIONS may cause this form of meningitis. Clinical manifestations include fever, headache, neck pain, vomiting, PHOTOPHOBIA, and signs of meningeal irritation. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3) Viral Meningitis,Meningitides, Viral,Viral Meningitides
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D004196 Disease Outbreaks Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS. Outbreaks,Infectious Disease Outbreaks,Disease Outbreak,Disease Outbreak, Infectious,Disease Outbreaks, Infectious,Infectious Disease Outbreak,Outbreak, Disease,Outbreak, Infectious Disease,Outbreaks, Disease,Outbreaks, Infectious Disease
D004457 Echovirus Infections Infectious disease processes, including meningitis, diarrhea, and respiratory disorders, caused by echoviruses. Echo Virus Infections,Infections, Echo Virus,Infections, Echovirus,Echo Virus Infection,Echovirus Infection,Infection, Echo Virus,Infection, Echovirus
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

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