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Episomal BK virus (BKV) DNA was detected in primary human brain tumours, in Kaposi's sarcoma and in cell lines from brain tumours. Ewing sarcoma and osteogenic sarcoma. Infectious BKV was rescued from several tumours and tumour cell lines by transfection of total cellular DNA into human embryonic fibroblasts. Restriction endonuclease and nucleotide sequence analysis showed that all the rescued viruses are similar to BKV-IR, a BK variant previously isolated from a human tumour of pancreatic islets, indicating that a specific BKV strain may be associated with certain types of human tumours. All the variants contain a putative transposable elements in the regulatory region of the viral genome. This region has mutagenic properties and enhancing activity in transformation, suggesting a possible role of these variants in tumour induction or progression.
M Negrini, and
P Rimessi, and
C Mantovani, and
S Sabbioni, and
A Corallini, and
M A Gerosa, and
G Barbanti-Brodano
January 1976,
Archives of virology,
M Negrini, and
P Rimessi, and
C Mantovani, and
S Sabbioni, and
A Corallini, and
M A Gerosa, and
G Barbanti-Brodano
September 2015,
Veterinary and comparative oncology,
M Negrini, and
P Rimessi, and
C Mantovani, and
S Sabbioni, and
A Corallini, and
M A Gerosa, and
G Barbanti-Brodano
August 1990,
Differentiation; research in biological diversity,
M Negrini, and
P Rimessi, and
C Mantovani, and
S Sabbioni, and
A Corallini, and
M A Gerosa, and
G Barbanti-Brodano
May 1980,
Virology,
M Negrini, and
P Rimessi, and
C Mantovani, and
S Sabbioni, and
A Corallini, and
M A Gerosa, and
G Barbanti-Brodano
June 2015,
Nature communications,
M Negrini, and
P Rimessi, and
C Mantovani, and
S Sabbioni, and
A Corallini, and
M A Gerosa, and
G Barbanti-Brodano
January 1975,
Folia biologica,
M Negrini, and
P Rimessi, and
C Mantovani, and
S Sabbioni, and
A Corallini, and
M A Gerosa, and
G Barbanti-Brodano
September 1989,
British journal of cancer,
M Negrini, and
P Rimessi, and
C Mantovani, and
S Sabbioni, and
A Corallini, and
M A Gerosa, and
G Barbanti-Brodano
March 1989,
The Biochemical journal,
M Negrini, and
P Rimessi, and
C Mantovani, and
S Sabbioni, and
A Corallini, and
M A Gerosa, and
G Barbanti-Brodano
January 1978,
Proceedings of the National Academy of Sciences of the United States of America,
M Negrini, and
P Rimessi, and
C Mantovani, and
S Sabbioni, and
A Corallini, and
M A Gerosa, and
G Barbanti-Brodano
March 1983,
British journal of cancer,
