Biomaterial Database

Blood flow velocity waveforms in the fetal cardiac outflow tract as a measure of fetal well-being in intrauterine growth retardation. 1990

I A Groenenberg, and T Stijnen, and J W Wladimiroff

Department of Obstetrics and Gynaecology, Erasmus University Rotterdam, The Netherlands.

Maximum flow velocity waveforms were recorded in a longitudinal study from the fetal ascending aorta and fetal pulmonary artery in 46 normal pregnancies and, in addition, from the umbilical artery in 21 cases of intrauterine growth retardation between 19 and 33 wk gestation. In normal pregnancy, the mean peak systolic velocity (PSV) in the ascending aorta increased from 49.4 cm/s at 19 wk of gestation to 79.0 cm/s at 33 wk of gestation. The corresponding increase in PSV in the pulmonary artery was from 39.0 to 63.7 cm/s. The ratio for the PSV between the two arteries remained constant (1.25-1.29). Mean values of PSV in both arteries were linearly related to gestational age. Normal limits according to age were constructed by establishing the 5th and 95th percentiles. In intrauterine growth retardation, the PSV in the pulmonary artery was decreased (less than 5th percentile) in 95% of cases, PSV in the ascending aorta was reduced (less than 5th percentile) in only 57%. No relationship was established between PSV in both arteries and the presence or absence of end-diastolic flow velocities in the umbilical artery. The outcome of fetuses with intrauterine growth retardation, as expressed by Apgar score at 1 min and umbilical cord pH, bears no relationship to the PSV in ascending aorta and pulmonary artery.

UI	MeSH Term	Description	Entries
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D011296	Prenatal Diagnosis	Determination of the nature of a pathological condition or disease in the postimplantation EMBRYO; FETUS; or pregnant female before birth.	Diagnosis, Prenatal,Fetal Diagnosis,Fetal Imaging,Fetal Screening,Intrauterine Diagnosis,Antenatal Diagnosis,Antenatal Screening,Diagnosis, Antenatal,Diagnosis, Intrauterine,Prenatal Screening,Antenatal Diagnoses,Antenatal Screenings,Diagnosis, Fetal,Fetal Diagnoses,Fetal Imagings,Fetal Screenings,Imaging, Fetal,Intrauterine Diagnoses,Prenatal Diagnoses,Prenatal Screenings,Screening, Antenatal,Screening, Fetal,Screening, Prenatal
D011651	Pulmonary Artery	The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs.	Arteries, Pulmonary,Artery, Pulmonary,Pulmonary Arteries
D001783	Blood Flow Velocity	A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.	Blood Flow Velocities,Flow Velocities, Blood,Flow Velocity, Blood,Velocities, Blood Flow,Velocity, Blood Flow
D002319	Cardiovascular System	The HEART and the BLOOD VESSELS by which BLOOD is pumped and circulated through the body.	Circulatory System,Cardiovascular Systems,Circulatory Systems
D005260	Female		Females
D005317	Fetal Growth Retardation	Failure of a FETUS to attain expected GROWTH.	Growth Retardation, Intrauterine,Intrauterine Growth Retardation,Fetal Growth Restriction,Intrauterine Growth Restriction
D005333	Fetus	The unborn young of a viviparous mammal, in the postembryonic period, after the major structures have been outlined. In humans, the unborn young from the end of the eighth week after CONCEPTION until BIRTH, as distinguished from the earlier EMBRYO, MAMMALIAN.	Fetal Structures,Fetal Tissue,Fetuses,Mummified Fetus,Retained Fetus,Fetal Structure,Fetal Tissues,Fetus, Mummified,Fetus, Retained,Structure, Fetal,Structures, Fetal,Tissue, Fetal,Tissues, Fetal
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults