Biomaterial Database

Results of intensified insulin therapy in type-I diabetics receiving instruction in self-monitoring. 1990

M Dryáková, and M Andĕl, and Z Slabochová, and V Bartos, and J Malý

Institute for Clinical and Experimental Medicine, Prague.

Therapeutic success in I-Type diabetes (i.e., glycaemia close to normal levels in an effort to influence favourably the onset and progression of long-term complications), two important preconditions must be met. The patient must receive instruction in safe self-monitoring so he could administer insulin under the supervision of health-care personnel, either using some of the conventional protocols or, in some cases, even unconventional intensified therapy. The aim of the latter approach is good compensation of diabetes and the well-being of a patient to whom insulin administration poses no inconvenience while sophisticated technology helps him or her to overcome stressful situations.

UI	MeSH Term	Description	Entries
D007328	Insulin	A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).	Iletin,Insulin A Chain,Insulin B Chain,Insulin, Regular,Novolin,Sodium Insulin,Soluble Insulin,Chain, Insulin B,Insulin, Sodium,Insulin, Soluble,Regular Insulin
D003922	Diabetes Mellitus, Type 1	A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.	Diabetes Mellitus, Brittle,Diabetes Mellitus, Insulin-Dependent,Diabetes Mellitus, Juvenile-Onset,Diabetes Mellitus, Ketosis-Prone,Diabetes Mellitus, Sudden-Onset,Diabetes, Autoimmune,IDDM,Autoimmune Diabetes,Diabetes Mellitus, Insulin-Dependent, 1,Diabetes Mellitus, Type I,Insulin-Dependent Diabetes Mellitus 1,Juvenile-Onset Diabetes,Type 1 Diabetes,Type 1 Diabetes Mellitus,Brittle Diabetes Mellitus,Diabetes Mellitus, Insulin Dependent,Diabetes Mellitus, Juvenile Onset,Diabetes Mellitus, Ketosis Prone,Diabetes Mellitus, Sudden Onset,Diabetes, Juvenile-Onset,Diabetes, Type 1,Insulin Dependent Diabetes Mellitus 1,Insulin-Dependent Diabetes Mellitus,Juvenile Onset Diabetes,Juvenile-Onset Diabetes Mellitus,Ketosis-Prone Diabetes Mellitus,Sudden-Onset Diabetes Mellitus
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D015190	Blood Glucose Self-Monitoring	Self evaluation of whole blood glucose levels outside the clinical laboratory. A digital or battery-operated reflectance meter may be used. It has wide application in controlling unstable insulin-dependent diabetes.	Blood Sugar Self-Monitoring,Home Blood Glucose Monitoring,Monitoring, Home Blood Glucose,Self-Monitoring, Blood Glucose,Glucose, Blood, Self Monitoring,Glucose, Blood, Self-Monitoring,Blood Glucose Self Monitoring,Blood Glucose Self-Monitorings,Blood Sugar Self Monitoring,Blood Sugar Self-Monitorings,Glucose Self-Monitoring, Blood,Glucose Self-Monitorings, Blood,Self Monitoring, Blood Glucose,Self-Monitoring, Blood Sugar,Self-Monitorings, Blood Glucose,Self-Monitorings, Blood Sugar,Sugar Self-Monitoring, Blood,Sugar Self-Monitorings, Blood