Flow-regulated continuous positive airway pressure to minimize imposed work of breathing. 1990

M Akashi, and K Sakanaka, and H Noguchi, and Y Takumi
Department of Anesthesiology and Acute Medicine, Aichi Medical University Hospital, Japan.

We have developed a new continuous positive airway pressure (CPAP) system, which consists of an electropneumatic regulator, a microcomputer, and a pneumotachograph placed between the endotracheal tube and the breathing circuit of the CPAP apparatus. This flow-regulated CPAP (FR-CPAP) system delivers a basal flow and also regulates this flow every 20 msec to match the patient's flow demand. To evaluate the performance of this FR-CPAP system, we compared the imposed work of breathing of the FR-CPAP and continuous flow CPAP (CF-CPAP) systems. A model lung was used to simulate spontaneous breathing. The imposed work of breathing of the FR-CPAP system was less than that of the CF-CPAP system. These results indicate that the FR-CPAP system could minimize the imposed work of breathing of a patient receiving CPAP.

UI MeSH Term Description Entries
D008961 Models, Structural A representation, generally small in scale, to show the structure, construction, or appearance of something. (From Random House Unabridged Dictionary, 2d ed) Model, Structural,Structural Model,Structural Models
D011175 Positive-Pressure Respiration A method of mechanical ventilation in which pressure is maintained to increase the volume of gas remaining in the lungs at the end of expiration, thus reducing the shunting of blood through the lungs and improving gas exchange. Positive End-Expiratory Pressure,Positive-Pressure Ventilation,End-Expiratory Pressure, Positive,End-Expiratory Pressures, Positive,Positive End Expiratory Pressure,Positive End-Expiratory Pressures,Positive Pressure Respiration,Positive Pressure Ventilation,Positive-Pressure Respirations,Positive-Pressure Ventilations,Pressure, Positive End-Expiratory,Pressures, Positive End-Expiratory,Respiration, Positive-Pressure,Respirations, Positive-Pressure,Ventilation, Positive-Pressure,Ventilations, Positive-Pressure
D014939 Work of Breathing RESPIRATORY MUSCLE contraction during INHALATION. The work is accomplished in three phases: LUNG COMPLIANCE work, that required to expand the LUNGS against its elastic forces; tissue resistance work, that required to overcome the viscosity of the lung and chest wall structures; and AIRWAY RESISTANCE work, that required to overcome airway resistance during the movement of air into the lungs. Work of breathing does not refer to expiration, which is entirely a passive process caused by elastic recoil of the lung and chest cage. (Guyton, Textbook of Medical Physiology, 8th ed, p406) Breathing Work,Breathing Works

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