Biomaterial Database

Basic data related to endovascular management of peripheral arterial disease in critical limb ischemia. 2012

Sridhar Venkatachalam, and Mehdi H Shishehbor, and Bruce H Gray

Department of Medicine, Cleveland Clinic, Cleveland, OH, USA.

Chronic critical limb ischemia occurs in the setting of severe peripheral arterial disease that is often characterized by advanced atherosclerosis at multiple levels in the lower extremity. Despite the challenges posed by the complexity of arterial disease in such patients, endovascular intervention is a less invasive alternative to infrainguinal bypass graft surgery in most patients, with low procedural morbidity and mortality. Continual advances in percutaneous techniques have made it possible to revascularize lesions considered nonamenable for endovascular intervention. For example, the development of dedicated peripheral wires, balloons, stents, and catheters allows the recanalization and revascularization of almost any anatomy. Pharmaceutical advances in risk factor modification for recurrent stenosis impact results. Such evolution makes data comparison difficult. This review aims to present the available data on endovascular therapy in critical limb ischemia patients reported over the past 2 decades.

UI	MeSH Term	Description	Entries
D007511	Ischemia	A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.	Ischemias
D011474	Prosthesis Design	The plan and delineation of prostheses in general or a specific prosthesis.	Design, Prosthesis,Designs, Prosthesis,Prosthesis Designs
D012008	Recurrence	The return of a sign, symptom, or disease after a remission.	Recrudescence,Relapse,Recrudescences,Recurrences,Relapses
D003251	Constriction, Pathologic	The condition of an anatomical structure's being constricted beyond normal dimensions.	Stenosis,Stricture,Constriction, Pathological,Pathologic Constriction,Constrictions, Pathologic,Pathologic Constrictions,Pathological Constriction,Stenoses,Strictures
D004867	Equipment Design	Methods and patterns of fabricating machines and related hardware.	Design, Equipment,Device Design,Medical Device Design,Design, Medical Device,Designs, Medical Device,Device Design, Medical,Device Designs, Medical,Medical Device Designs,Design, Device,Designs, Device,Designs, Equipment,Device Designs,Equipment Designs
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000800	Angioplasty, Balloon	Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.	Balloon Angioplasty,Dilation, Transluminal Arterial,Arterial Dilation, Transluminal,Arterial Dilations, Transluminal,Dilations, Transluminal Arterial,Transluminal Arterial Dilation,Transluminal Arterial Dilations
D012307	Risk Factors	An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent.	Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor
D015607	Stents	Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.	Stent
D016638	Critical Illness	A disease or state in which death is possible or imminent.	Critically Ill,Critical Illnesses,Illness, Critical,Illnesses, Critical