Biomaterial Database

Hydrocarbon monooxygenase system of Pseudomonas oleovorans. 1990

S W May, and A G Katopodis

UI	MeSH Term	Description	Entries
D011549	Pseudomonas	A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in nature. Some species are pathogenic for humans, animals, and plants.	Chryseomonas,Pseudomona,Flavimonas
D003577	Cytochrome P-450 Enzyme System	A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism.	Cytochrome P-450,Cytochrome P-450 Enzyme,Cytochrome P-450-Dependent Monooxygenase,P-450 Enzyme,P450 Enzyme,CYP450 Family,CYP450 Superfamily,Cytochrome P-450 Enzymes,Cytochrome P-450 Families,Cytochrome P-450 Monooxygenase,Cytochrome P-450 Oxygenase,Cytochrome P-450 Superfamily,Cytochrome P450,Cytochrome P450 Superfamily,Cytochrome p450 Families,P-450 Enzymes,P450 Enzymes,Cytochrome P 450,Cytochrome P 450 Dependent Monooxygenase,Cytochrome P 450 Enzyme,Cytochrome P 450 Enzyme System,Cytochrome P 450 Enzymes,Cytochrome P 450 Families,Cytochrome P 450 Monooxygenase,Cytochrome P 450 Oxygenase,Cytochrome P 450 Superfamily,Enzyme, Cytochrome P-450,Enzyme, P-450,Enzyme, P450,Enzymes, Cytochrome P-450,Enzymes, P-450,Enzymes, P450,Monooxygenase, Cytochrome P-450,Monooxygenase, Cytochrome P-450-Dependent,P 450 Enzyme,P 450 Enzymes,P-450 Enzyme, Cytochrome,P-450 Enzymes, Cytochrome,Superfamily, CYP450,Superfamily, Cytochrome P-450,Superfamily, Cytochrome P450
D006899	Mixed Function Oxygenases	Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation.	Hydroxylase,Hydroxylases,Mixed Function Oxidase,Mixed Function Oxygenase,Monooxygenase,Monooxygenases,Mixed Function Oxidases,Function Oxidase, Mixed,Function Oxygenase, Mixed,Oxidase, Mixed Function,Oxidases, Mixed Function,Oxygenase, Mixed Function,Oxygenases, Mixed Function
D012416	Rubredoxins	A class of iron-sulfur proteins that contains one iron coordinated to the sulfur atom of four cysteine residues. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)	Rubredoxin
D042926	Cytochrome P-450 CYP4A	A P450 oxidoreductase that catalyzes the hydroxylation of the terminal carbon of linear hydrocarbons such as OCTANES and FATTY ACIDS in the omega position. The enzyme may also play a role in the oxidation of a variety of structurally unrelated compounds such as XENOBIOTICS, and STEROIDS.	Alkane 1-Monooxygenase,Lauric Acid Hydroxylase,Alkane 1-Hydroxylase,Alkane Hydroxylase,CYP4A,Cytochrome P-450 4A,Cytochrome P-450 IVA,Fatty Acid Omega-Hydroxylase,Laurate Omega-Hydroxylase,Lauric Acid (Omega-1)-Hydroxylase,Lauric Acid Monooxygenase,Lauric Acid Omega-hydroxylase,Omega-1 Hydroxylase,Omega-Hydroxylase,Omega-Lauryl Hydroxylase,Acid Hydroxylase, Lauric,Acid Omega-Hydroxylase, Fatty,Acid Omega-hydroxylase, Lauric,Alkane 1 Hydroxylase,Alkane 1 Monooxygenase,CYP4A, Cytochrome P-450,Cytochrome P 450 4A,Cytochrome P 450 CYP4A,Cytochrome P 450 IVA,Fatty Acid Omega Hydroxylase,Hydroxylase, Alkane,Hydroxylase, Omega-1,Hydroxylase, Omega-Lauryl,Laurate Omega Hydroxylase,Lauric Acid Omega hydroxylase,Omega 1 Hydroxylase,Omega Hydroxylase,Omega Lauryl Hydroxylase,Omega-Hydroxylase, Fatty Acid,Omega-Hydroxylase, Laurate,Omega-hydroxylase, Lauric Acid,P-450 4A, Cytochrome,P-450 CYP4A, Cytochrome