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Myostatin, or growth and differentiation factor 8, is a member of the transforming growth factor-β superfamily; it functions as a negative regulator of skeletal muscle development and growth in mammals. In this study, single nucleotide polymorphisms in the 5' regulatory region and exon 1 of the myostatin gene were detected by PCR-SSCP in the Bian, Jinghai, Youxi, and Arbor Acre chickens, and the associations of the polymorphisms with reproduction traits were analyzed. Seven SNPs (A326G, C334G, C1346T, G1375A, A1473G, G1491A, and G2283A) were found in the myostatin gene. Association analysis showed that the G2283A were significantly associated with reproduction traits. Bian chickens of the GG genotype had a greater age at first egg than those of the GA and AA genotypes (P<0.01). Correspondingly, Bian chickens of the GA and AA genotypes had larger egg number at 300 days than those of the GG genotype (P<0.05 and P<0.01, respectively). Bian chickens of the AA genotype had significantly higher body weight at 300 days than those of the GG genotype (P<0.05). These results suggested that the myostatin gene may have certain effects on reproduction traits other than merely as a negative regulator of skeletal muscle development and growth in mammals previously reported.
Genxi Zhang, and
Li Zhang, and
Yue Wei, and
Jinyu Wang, and
Fuxiang Ding, and
Guojun Dai, and
Kaizhou Xie
April 2013,
Poultry science,
Genxi Zhang, and
Li Zhang, and
Yue Wei, and
Jinyu Wang, and
Fuxiang Ding, and
Guojun Dai, and
Kaizhou Xie
January 2023,
Pakistan journal of biological sciences : PJBS,
Genxi Zhang, and
Li Zhang, and
Yue Wei, and
Jinyu Wang, and
Fuxiang Ding, and
Guojun Dai, and
Kaizhou Xie
October 2016,
Animal biotechnology,
Genxi Zhang, and
Li Zhang, and
Yue Wei, and
Jinyu Wang, and
Fuxiang Ding, and
Guojun Dai, and
Kaizhou Xie
May 2007,
Yi chuan = Hereditas,
Genxi Zhang, and
Li Zhang, and
Yue Wei, and
Jinyu Wang, and
Fuxiang Ding, and
Guojun Dai, and
Kaizhou Xie
April 2022,
Animals : an open access journal from MDPI,
Genxi Zhang, and
Li Zhang, and
Yue Wei, and
Jinyu Wang, and
Fuxiang Ding, and
Guojun Dai, and
Kaizhou Xie
May 2012,
Poultry science,
Genxi Zhang, and
Li Zhang, and
Yue Wei, and
Jinyu Wang, and
Fuxiang Ding, and
Guojun Dai, and
Kaizhou Xie
January 2007,
Genetics, selection, evolution : GSE,
Genxi Zhang, and
Li Zhang, and
Yue Wei, and
Jinyu Wang, and
Fuxiang Ding, and
Guojun Dai, and
Kaizhou Xie
January 2021,
Reproduction in domestic animals = Zuchthygiene,
Genxi Zhang, and
Li Zhang, and
Yue Wei, and
Jinyu Wang, and
Fuxiang Ding, and
Guojun Dai, and
Kaizhou Xie
April 2014,
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie,
Genxi Zhang, and
Li Zhang, and
Yue Wei, and
Jinyu Wang, and
Fuxiang Ding, and
Guojun Dai, and
Kaizhou Xie
November 2019,
Animal reproduction science,
