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Characterization of a Low Pathogenic Avian Influenza Virus (H6N1) Isolated from Turkeys. 2011

I Shkoda, and E Lapin, and E Rosenbluth, and S Perk, and Z Geva, and A Inbar, and I Davidson
Division of Avian Diseases, Kimron Veterinary Institute, P.O. Box 12, Bet Dagan 50250, Israel.

An avian influenza virus (AIV), A/turkey/Israel/09 subtype H6N1, was isolated from turkey poults exhibiting typical pathology associated with AIV infection. The virus was characterized by RT-PCR using AIV subtype-specific primers and by the haemagglutination inhibition test using AIV subtype-specific antisera. The virus has an intravenous pathogenicity index of 0 and possessed a nucleotide sequence at the cleavage site of the hemagglutinin gene, PQIETR*GLF, associated with avian influenza viruses of low pathogenicity. Unlike the two previous H6N2 isolates originating from domestic ducks and mallard, the A/turkey/Israel/09 (H6N1) was isolated from turkeys. The gene sequences of the A/turkey/Israel/09 (H6N1) virus show divergence from the former Israeli H6 isolates.

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