[Acute kidney insufficiency in ethylene glycol poisoning]. 1990

S Nogué, and J Campistol, and A Torras, and P Munné, and L Revert
Unidad de Coordinación Toxicológica, Hospital Clinic i Provincial, Barcelona.

A case of severe ethylene-glycol intoxication is presented in which there were potentially fatal plasma levels, neurological manifestations and acute renal failure and which was treated with ethanol and hemodialysis. Crystal deposits, normal glomeruli and severe tubular affectation suggestive of direct cytotoxic action, were found in renal biopsy, which was performed during the anuric phase. The evolution was favorable with no neurologic sequelae, diuresis re-onset on day 17 and return of normal renal function.

UI MeSH Term Description Entries
D007668 Kidney Body organ that filters blood for the secretion of URINE and that regulates ion concentrations. Kidneys
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D005026 Ethylene Glycols An ethylene compound with two hydroxy groups (-OH) located on adjacent carbons. They are viscous and colorless liquids. Some are used as anesthetics or hypnotics. However, the class is best known for their use as a coolant or antifreeze. Dihydroxyethanes,Ethanediols,Glycols, Ethylene
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001706 Biopsy Removal and pathologic examination of specimens from the living body. Biopsies
D058186 Acute Kidney Injury Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. Acute Kidney Failure,Acute Kidney Insufficiency,Acute Renal Failure,Acute Renal Injury,Acute Renal Insufficiency,Kidney Failure, Acute,Kidney Insufficiency, Acute,Renal Failure, Acute,Renal Insufficiency, Acute,Acute Kidney Failures,Acute Kidney Injuries,Acute Kidney Insufficiencies,Acute Renal Failures,Acute Renal Injuries,Acute Renal Insufficiencies,Kidney Failures, Acute,Kidney Injuries, Acute,Kidney Injury, Acute,Kidney Insufficiencies, Acute,Renal Failures, Acute,Renal Injuries, Acute,Renal Injury, Acute,Renal Insufficiencies, Acute
D019855 Ethylene Glycol A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins. 1,2-Ethanediol,2-Hydroxyethanol,Monoethylene Glycol,1,2 Ethanediol,2 Hydroxyethanol,Glycol, Ethylene,Glycol, Monoethylene

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