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In 37 patients with clinically suspected non-specific bronchial hyperreactivity, a comparative study was performed prior to and following bronchial challenge with histamine employing the following parameters: flow-volume curve, whole-body plethysmography, single-breath spirometry, capillary blood gas analysis. Four types of reaction can be distinguished: isolated bronchial reaction, isolated gas transfer disturbance, dual reaction, no reaction. A Correlation of the induced gas transfer disturbance was found only for the flow data reflecting small airways dysfunction (Vmax 25%), but not for the basic lung function parameters. The transfer factor and transfer coefficient are insensitive and, on average, show only small, non-directed changes.
R Schultebraucks, and
W Frank, and
R Loddenkemper
August 1986,
American journal of veterinary research,
R Schultebraucks, and
W Frank, and
R Loddenkemper
January 1998,
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R Schultebraucks, and
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R Loddenkemper
January 1984,
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R Schultebraucks, and
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May 1982,
Die Medizinische Welt,
R Schultebraucks, and
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R Schultebraucks, and
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R Loddenkemper
November 1989,
The Journal of allergy and clinical immunology,
R Schultebraucks, and
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R Loddenkemper
December 1986,
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R Schultebraucks, and
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R Loddenkemper
January 1994,
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R Schultebraucks, and
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R Loddenkemper
November 2000,
Chest,
R Schultebraucks, and
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R Loddenkemper
July 1974,
Monatsschrift fur Kinderheilkunde,
