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The peripheral blood lymphocyte response of patients with ankylosing spondylitis (AS) to several polyclonal B cell activators was investigated. No differences were found in the reactivity to pokeweed mitogen and protein A between patients and controls; in contrast, the peripheral blood lymphocyte response to Staphylococcus aureus strain Cowan I (SAC) was significantly higher in patients with AS than in controls. This responsiveness was not influenced either by the presence of the HLA-B27 antigen or by environmental factors or associated diseases, and it was higher in patients with active AS than in those with inactive disease. The percentage of circulating B cells was normal. The responses to T cell mitogens and the percentages of T cell subpopulations were similar in patients and in controls. The peripheral blood lymphocyte hyperactivity of patients with AS to SAC was associated with an increased in vitro production of immunoglobulins.
P Barbieri, and
I Olivieri, and
G Benedettini, and
P Marelli, and
M L Ciompi, and
G Pasero, and
M Campa
November 2013,
Life sciences,
P Barbieri, and
I Olivieri, and
G Benedettini, and
P Marelli, and
M L Ciompi, and
G Pasero, and
M Campa
November 1989,
Mycopathologia,
P Barbieri, and
I Olivieri, and
G Benedettini, and
P Marelli, and
M L Ciompi, and
G Pasero, and
M Campa
July 1989,
Journal of periodontal research,
P Barbieri, and
I Olivieri, and
G Benedettini, and
P Marelli, and
M L Ciompi, and
G Pasero, and
M Campa
December 2021,
International journal of molecular sciences,
P Barbieri, and
I Olivieri, and
G Benedettini, and
P Marelli, and
M L Ciompi, and
G Pasero, and
M Campa
September 1983,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
P Barbieri, and
I Olivieri, and
G Benedettini, and
P Marelli, and
M L Ciompi, and
G Pasero, and
M Campa
February 1992,
Lupus,
P Barbieri, and
I Olivieri, and
G Benedettini, and
P Marelli, and
M L Ciompi, and
G Pasero, and
M Campa
December 1995,
International journal of hematology,
P Barbieri, and
I Olivieri, and
G Benedettini, and
P Marelli, and
M L Ciompi, and
G Pasero, and
M Campa
April 1978,
Clinical and experimental immunology,
P Barbieri, and
I Olivieri, and
G Benedettini, and
P Marelli, and
M L Ciompi, and
G Pasero, and
M Campa
October 2003,
Nature immunology,
P Barbieri, and
I Olivieri, and
G Benedettini, and
P Marelli, and
M L Ciompi, and
G Pasero, and
M Campa
January 2015,
PloS one,
