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A human hepatoma cell line, associated with thorotrast exposure, from an hepatitis B marker-negative patient was established as a permanent cell line (Mz-Hep-1) in tissue culture. Histology of the primary tumor, as well as phase contrast, transmission and scanning electron microscopy of the cultured cells showed typical characteristics of liver cells. Mz-Hep-1 cells secreted complement components (C2, C3, C4), carcinoembryonic antigen, lactate dehydrogenase, chymotrypsin, haptoglobin and retinol-binding protein and expressed HLA-, transferrin-, blood group B-related determinants and complement component C5 and carcinoembryonic antigen on their cell surface. Mz-Hep-1 cells represent the first human hepatoma cell line, which is strongly associated with a carcinogen.
W G Dippold, and
H P Dienes, and
A Knuth, and
W Sachsse, and
W Prellwitz, and
D Bitter-Suermann, and
K H Meyer zum Büschenfelde
January 2023,
Human cell,
W G Dippold, and
H P Dienes, and
A Knuth, and
W Sachsse, and
W Prellwitz, and
D Bitter-Suermann, and
K H Meyer zum Büschenfelde
January 1988,
Hepatology (Baltimore, Md.),
W G Dippold, and
H P Dienes, and
A Knuth, and
W Sachsse, and
W Prellwitz, and
D Bitter-Suermann, and
K H Meyer zum Büschenfelde
June 1984,
In vitro,
W G Dippold, and
H P Dienes, and
A Knuth, and
W Sachsse, and
W Prellwitz, and
D Bitter-Suermann, and
K H Meyer zum Büschenfelde
January 1985,
Hepatology (Baltimore, Md.),
W G Dippold, and
H P Dienes, and
A Knuth, and
W Sachsse, and
W Prellwitz, and
D Bitter-Suermann, and
K H Meyer zum Büschenfelde
September 1995,
The Tohoku journal of experimental medicine,
W G Dippold, and
H P Dienes, and
A Knuth, and
W Sachsse, and
W Prellwitz, and
D Bitter-Suermann, and
K H Meyer zum Büschenfelde
March 1988,
Japanese journal of cancer research : Gann,
W G Dippold, and
H P Dienes, and
A Knuth, and
W Sachsse, and
W Prellwitz, and
D Bitter-Suermann, and
K H Meyer zum Büschenfelde
August 1987,
Cancer research,
W G Dippold, and
H P Dienes, and
A Knuth, and
W Sachsse, and
W Prellwitz, and
D Bitter-Suermann, and
K H Meyer zum Büschenfelde
December 2024,
Bioengineered,
W G Dippold, and
H P Dienes, and
A Knuth, and
W Sachsse, and
W Prellwitz, and
D Bitter-Suermann, and
K H Meyer zum Büschenfelde
September 1991,
The Journal of urology,
W G Dippold, and
H P Dienes, and
A Knuth, and
W Sachsse, and
W Prellwitz, and
D Bitter-Suermann, and
K H Meyer zum Büschenfelde
August 1983,
International journal of cancer,
