The effects of time-to-surgery on mortality in elderly patients following hip fractures. 2013

Simon Trpeski, and Igor Kaftandziev, and Aleko Kjaev
University Traumatology Clinic, Medical Faculty, Ss. Cyril and Methodius University, Skopje, R. Macedonia.

BACKGROUND Mortality occurring as a consequence of hip fracture in older patients is very high. Mortality is highest in the first few months after the injury, and this rate is kept at a high level within the first six months postoperatively. Current guidelines indicate that surgery should be performed within 48 hours of injury because early surgery is associated with lower rates of perioperative complications and mortality. OBJECTIVE To analyse the effects of time-to-surgery on mortality in elderly patients with hip fracture. METHODS The research was conducted at the University Traumatology Clinic in Skopje, where 120 patients with hip fracture of age 65 and above were treated. The age span was 55-95 years, with a mean age of 73.9±9.8 years. The time frame for the research and the follow-up of the patients was 6 months. Inclusion criteria included patients aged above 65 and isolated proximal femur fractures. Survival time for patients after six months was determined with the Kaplan-Meier product-limit method. Statistical significance was evaluated at level of p<0.05. RESULTS The mean time from patient admission to surgical intervention was 3.07±1.5 days (range 0-6 days). Hospitalization time averaged 11±4.7 days. We separated our patient population into two groups, one consisting of patients operated in the first two days, the other after two days. The patient death rate in the first group of 25 patients operated in the first 48 hours was a total of 4 patients (16%) after 6 months. The second group, 95 patients operated after 48 hours, showed a significant rise in mortality--32 patients (33.7%). The mean survival time of patients operated within 48 hours is 168.8 days, while the mean survival time of patients operated after 48 hours from their hospital admission was 143.6 days. CONCLUSIONS Delay in surgery is associated with significant increase in mortality. Patients should have their operation as soon as possible after admission to hospital, preferably in the first 48 hours.

UI MeSH Term Description Entries
D007902 Length of Stay The period of confinement of a patient to a hospital or other health facility. Hospital Stay,Hospital Stays,Stay Length,Stay Lengths,Stay, Hospital,Stays, Hospital
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010343 Patient Admission The process of accepting patients. The concept includes patients accepted for medical and nursing care in a hospital or other health care institution. Voluntary Admission,Admission, Patient,Admission, Voluntary,Admissions, Patient,Admissions, Voluntary,Patient Admissions,Voluntary Admissions
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D005260 Female Females
D006620 Hip Fractures Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES). Femoral Trochlear Fractures,Intertrochanteric Fractures,Subtrochanteric Fractures,Trochanteric Fractures,Trochlear Fractures, Femur,Femoral Trochlear Fracture,Femur Trochlear Fracture,Femur Trochlear Fractures,Fracture, Femoral Trochlear,Fracture, Femur Trochlear,Fractures, Femoral Trochlear,Fractures, Femur Trochlear,Fractures, Hip,Fractures, Intertrochanteric,Fractures, Subtrochanteric,Fractures, Trochanteric,Trochlear Fracture, Femoral,Trochlear Fracture, Femur,Trochlear Fractures, Femoral
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000046 Academic Medical Centers Medical complexes consisting of medical school, hospitals, clinics, libraries, administrative facilities, etc. Medical Centers, Academic,Medical Centers, University,University Medical Centers,Academic Medical Center,Center, Academic Medical,Center, University Medical,Centers, Academic Medical,Centers, University Medical,Medical Center, Academic,Medical Center, University,University Medical Center
D000367 Age Factors Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time. Age Reporting,Age Factor,Factor, Age,Factors, Age

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