BIOMAT Database Logo BIOMAT Database Logo

Structure and chemistry of alkali-labile product formed during Fe(II)-bleomycin-mediated DNA strand scission. 1986

H Sugiyama, and T Morii, and I Saito, and T Matsuura, and S M Hecht

UI MeSH Term Description Entries
D009838 Oligodeoxyribonucleotides A group of deoxyribonucleotides (up to 12) in which the phosphate residues of each deoxyribonucleotide act as bridges in forming diester linkages between the deoxyribose moieties. Oligodeoxynucleotide,Oligodeoxyribonucleotide,Oligodeoxynucleotides
D001761 Bleomycin A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. BLEO-cell,Blanoxan,Blenoxane,Bleolem,Bleomicina,Bleomycin A(2),Bleomycin A2,Bleomycin B(2),Bleomycin B2,Bleomycin Sulfate,Bleomycins,Bleomycinum Mack,Bléomycine Bellon,BLEO cell,BLEOcell,Bellon, Bléomycine,Mack, Bleomycinum,Sulfate, Bleomycin
D004247 DNA A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine). DNA, Double-Stranded,Deoxyribonucleic Acid,ds-DNA,DNA, Double Stranded,Double-Stranded DNA,ds DNA
D006863 Hydrogen-Ion Concentration The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH pH,Concentration, Hydrogen-Ion,Concentrations, Hydrogen-Ion,Hydrogen Ion Concentration,Hydrogen-Ion Concentrations
D006868 Hydrolysis The process of cleaving a chemical compound by the addition of a molecule of water.

Related Publications

H Sugiyama, and T Morii, and I Saito, and T Matsuura, and S M Hecht
DNA methylation diminishes bleomycin-mediated strand scission.
September 1985, Biochemistry,
H Sugiyama, and T Morii, and I Saito, and T Matsuura, and S M Hecht
Chemistry of the alkali-labile lesion formed from iron(II) bleomycin and d(CGCTTTAAAGCG).
January 1988, Biochemistry,
H Sugiyama, and T Morii, and I Saito, and T Matsuura, and S M Hecht
Characterization of iron (II).bleomycin-mediated RNA strand scission.
April 1993, Biochemistry,
H Sugiyama, and T Morii, and I Saito, and T Matsuura, and S M Hecht
Site specificity of bleomycin-mediated single-strand scissions and alkali-labile damage in duplex DNA.
November 1979, Gene,
H Sugiyama, and T Morii, and I Saito, and T Matsuura, and S M Hecht
DNA double-strand breaks and alkali-labile bonds produced by bleomycin.
October 1977, Nucleic acids research,
H Sugiyama, and T Morii, and I Saito, and T Matsuura, and S M Hecht
Chemistry of oxidative DNA strand scission.
January 1993, Nucleic acids symposium series,
H Sugiyama, and T Morii, and I Saito, and T Matsuura, and S M Hecht
DNA strand scission by bleomycin group antibiotics.
January 1985, Journal of natural products,
H Sugiyama, and T Morii, and I Saito, and T Matsuura, and S M Hecht
Hemin-mediated DNA strand scission.
October 1983, The Journal of biological chemistry,
H Sugiyama, and T Morii, and I Saito, and T Matsuura, and S M Hecht
DNA strand scission by activated bleomycin group antibiotics.
November 1986, Federation proceedings,
H Sugiyama, and T Morii, and I Saito, and T Matsuura, and S M Hecht
Stoichiometry of DNA strand scission and aldehyde formation by bleomycin.
August 1982, The Journal of biological chemistry,
Copied contents to your clipboard!