pH-triggered formation of nanoribbons from yeast-derived glycolipid biosurfactants. 2014

Anne-Sophie Cuvier, and Jan Berton, and Christian V Stevens, and Giulia C Fadda, and Florence Babonneau, and Inge N A Van Bogaert, and Wim Soetaert, and Gérard Pehau-Arnaudet, and Niki Baccile
Sorbonne Universités, UPMC Univ Paris 06, UMR 7574, Chimie de la Matière Condensée de Paris, F-75005, Paris, France. niki.baccile@upmc.fr.

In the present paper, we show that the saturated form of acidic sophorolipids, a family of industrially scaled bolaform microbial glycolipids, unexpectedly forms chiral nanofibers only at pH below 7.5. In particular, we illustrate that this phenomenon derives from a subtle cooperative effect of molecular chirality, hydrogen bonding, van der Waals forces and steric hindrance. The pH-responsive behaviour was shown by Dynamic Light Scattering (DLS), pH-titration and Field Emission Scanning Electron Microscopy (FE-SEM) while the nanoscale chirality was evidenced by Circular Dichroism (CD) and cryo Transmission Electron Microscopy (cryo-TEM). The packing of sophorolipids within the ribbons was studied using Small Angle Neutron Scattering (SANS), Wide Angle X-ray Scattering (WAXS) and 2D (1)H-(1)H through-space correlations via Nuclear Magnetic Resonance under very fast (67 kHz) Magic Angle Spinning (MAS-NMR).

UI MeSH Term Description Entries
D008968 Molecular Conformation The characteristic three-dimensional shape of a molecule. Molecular Configuration,3D Molecular Structure,Configuration, Molecular,Molecular Structure, Three Dimensional,Three Dimensional Molecular Structure,3D Molecular Structures,Configurations, Molecular,Conformation, Molecular,Conformations, Molecular,Molecular Configurations,Molecular Conformations,Molecular Structure, 3D,Molecular Structures, 3D,Structure, 3D Molecular,Structures, 3D Molecular
D002942 Circular Dichroism A change from planar to elliptic polarization when an initially plane-polarized light wave traverses an optically active medium. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Circular Dichroism, Vibrational,Dichroism, Circular,Vibrational Circular Dichroism
D006017 Glycolipids Any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic moiety such as an acylglycerol (see GLYCERIDES), a sphingoid, a ceramide (CERAMIDES) (N-acylsphingoid) or a prenyl phosphate. (From IUPAC's webpage) Glycolipid
D006860 Hydrogen Bonding A low-energy attractive force between hydrogen and another element. It plays a major role in determining the properties of water, proteins, and other compounds. Hydrogen Bonds,Bond, Hydrogen,Hydrogen Bond
D006863 Hydrogen-Ion Concentration The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH pH,Concentration, Hydrogen-Ion,Concentrations, Hydrogen-Ion,Hydrogen Ion Concentration,Hydrogen-Ion Concentrations
D012441 Saccharomyces cerevisiae A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement. Baker's Yeast,Brewer's Yeast,Candida robusta,S. cerevisiae,Saccharomyces capensis,Saccharomyces italicus,Saccharomyces oviformis,Saccharomyces uvarum var. melibiosus,Yeast, Baker's,Yeast, Brewer's,Baker Yeast,S cerevisiae,Baker's Yeasts,Yeast, Baker
D013237 Stereoisomerism The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed) Molecular Stereochemistry,Stereoisomers,Stereochemistry, Molecular,Stereoisomer
D013501 Surface-Active Agents Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics. Surface Active Agent,Surface-Active Agent,Surfactant,Surfactants,Tenside,Amphiphilic Agents,Surface Active Agents,Tensides,Active Agent, Surface,Active Agents, Surface,Agent, Surface Active,Agent, Surface-Active,Agents, Amphiphilic,Agents, Surface Active,Agents, Surface-Active
D055672 Static Electricity The accumulation of an electric charge on a object Electrostatic,Electrostatics,Static Charge,Charge, Static,Charges, Static,Electricity, Static,Static Charges
D057139 Nanofibers Submicron-sized fibers with diameters typically between 50 and 500 nanometers. The very small dimension of these fibers can generate a high surface area to volume ratio, which makes them potential candidates for various biomedical and other applications. Nanofiber

Related Publications

Anne-Sophie Cuvier, and Jan Berton, and Christian V Stevens, and Giulia C Fadda, and Florence Babonneau, and Inge N A Van Bogaert, and Wim Soetaert, and Gérard Pehau-Arnaudet, and Niki Baccile
April 2018, FEBS letters,
Anne-Sophie Cuvier, and Jan Berton, and Christian V Stevens, and Giulia C Fadda, and Florence Babonneau, and Inge N A Van Bogaert, and Wim Soetaert, and Gérard Pehau-Arnaudet, and Niki Baccile
January 2004, Journal of applied microbiology,
Anne-Sophie Cuvier, and Jan Berton, and Christian V Stevens, and Giulia C Fadda, and Florence Babonneau, and Inge N A Van Bogaert, and Wim Soetaert, and Gérard Pehau-Arnaudet, and Niki Baccile
August 2009, Journal of bioscience and bioengineering,
Anne-Sophie Cuvier, and Jan Berton, and Christian V Stevens, and Giulia C Fadda, and Florence Babonneau, and Inge N A Van Bogaert, and Wim Soetaert, and Gérard Pehau-Arnaudet, and Niki Baccile
June 2017, Colloids and surfaces. B, Biointerfaces,
Anne-Sophie Cuvier, and Jan Berton, and Christian V Stevens, and Giulia C Fadda, and Florence Babonneau, and Inge N A Van Bogaert, and Wim Soetaert, and Gérard Pehau-Arnaudet, and Niki Baccile
June 2011, Journal of bioscience and bioengineering,
Anne-Sophie Cuvier, and Jan Berton, and Christian V Stevens, and Giulia C Fadda, and Florence Babonneau, and Inge N A Van Bogaert, and Wim Soetaert, and Gérard Pehau-Arnaudet, and Niki Baccile
September 2013, Sheng wu gong cheng xue bao = Chinese journal of biotechnology,
Anne-Sophie Cuvier, and Jan Berton, and Christian V Stevens, and Giulia C Fadda, and Florence Babonneau, and Inge N A Van Bogaert, and Wim Soetaert, and Gérard Pehau-Arnaudet, and Niki Baccile
March 2007, FEMS yeast research,
Anne-Sophie Cuvier, and Jan Berton, and Christian V Stevens, and Giulia C Fadda, and Florence Babonneau, and Inge N A Van Bogaert, and Wim Soetaert, and Gérard Pehau-Arnaudet, and Niki Baccile
July 2006, Yeast (Chichester, England),
Anne-Sophie Cuvier, and Jan Berton, and Christian V Stevens, and Giulia C Fadda, and Florence Babonneau, and Inge N A Van Bogaert, and Wim Soetaert, and Gérard Pehau-Arnaudet, and Niki Baccile
August 2017, Biochemistry,
Anne-Sophie Cuvier, and Jan Berton, and Christian V Stevens, and Giulia C Fadda, and Florence Babonneau, and Inge N A Van Bogaert, and Wim Soetaert, and Gérard Pehau-Arnaudet, and Niki Baccile
June 2003, Journal of biomedical materials research. Part A,
Copied contents to your clipboard!