Biomaterial Database

Foveal ablation for subfoveal choroidal neovascularization. 1989

E E Boldrey

Palo Alto Medical Foundation, CA 94301.

Untreated subfoveal choroidal neovascularization (SFCN) often progresses to destroy much central visual function. In this study, laser photocoagulation which included the entire foveal avascular zone was applied to SFCN in the second eye of 13 consecutive patients. Each patient had untreated SFCN in their first eye with visual acuity less than or equal to 20/400. Each second eye had SFCN of recent onset which was less than or equal to 1 disc diameter (DD) in size and visual acuity less than or equal to 20/200. In 10 of 13 (76.9%) treated eyes, SFCN was eliminated for 3 to 30 months. These eyes all retained strikingly better visual fields (Amsler or automated) than their fellow untreated eyes, markedly better subjective vision, and Snellen visual acuities of 20/70 to 20/400. Foveal photocoagulation may be useful in selected cases of SFCN with small neovascular nets and poor visual acuity.

UI	MeSH Term	Description	Entries
D008028	Light Coagulation	The coagulation of tissue by an intense beam of light, including laser (LASER COAGULATION). In the eye it is used in the treatment of retinal detachments, retinal holes, aneurysms, hemorrhages, and malignant and benign neoplasms. (Dictionary of Visual Science, 3d ed)	Photocoagulation,Coagulation, Light,Coagulations, Light,Light Coagulations,Photocoagulations
D008266	Macula Lutea	An oval area in the retina, 3 to 5 mm in diameter, usually located temporal to the posterior pole of the eye and slightly below the level of the optic disk. It is characterized by the presence of a yellow pigment diffusely permeating the inner layers, contains the fovea centralis in its center, and provides the best phototropic visual acuity. It is devoid of retinal blood vessels, except in its periphery, and receives nourishment from the choriocapillaris of the choroid. (From Cline et al., Dictionary of Visual Science, 4th ed)	Lutea, Macula,Luteas, Macula,Macula Luteas
D008297	Male		Males
D009389	Neovascularization, Pathologic	A pathologic process consisting of the proliferation of blood vessels in abnormal tissues or in abnormal positions.	Angiogenesis, Pathologic,Angiogenesis, Pathological,Neovascularization, Pathological,Pathologic Angiogenesis,Pathologic Neovascularization,Pathological Angiogenesis,Pathological Neovascularization
D002829	Choroid	The thin, highly vascular membrane covering most of the posterior of the eye between the RETINA and SCLERA.	Choriocapillaris,Haller Layer,Haller's Layer,Sattler Layer,Sattler's Layer,Choroids
D005260	Female		Females
D005451	Fluorescein Angiography	Visualization of a vascular system after intravenous injection of a fluorescein solution. The images may be photographed or televised. It is used especially in studying the retinal and uveal vasculature.	Fluorescence Angiography,Fundus Fluorescence Photography,Angiography, Fluorescein,Angiography, Fluorescence,Fluorescence Photography, Fundus,Photography, Fundus Fluorescence
D005584	Fovea Centralis	An area approximately 1.5 millimeters in diameter within the macula lutea where the retina thins out greatly because of the oblique shifting of all layers except the pigment epithelium layer. It includes the sloping walls of the fovea (clivus) and contains a few rods in its periphery. In its center (foveola) are the cones most adapted to yield high visual acuity, each cone being connected to only one ganglion cell. (Cline et al., Dictionary of Visual Science, 4th ed)
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly