Biomaterial Database

[New results in computer simulation of the spread of excitation in the myocardium]. 1989

V Szathmáry

The paper presents the results from three series of simulation experiments performed by means of a realistic computer model of activation propagation in the myocardium. Simulation of two types of hypertrophy showed that hypertrophy of the ventricles without their simultaneous dilatation leaves the parameters of the cardioelectric field virtually unchanged. Change in the activation rate in the layer of elements formed by the intraventricular surface of the cavities, compared to the rate in the other elements of the heart, considerably affects the magnitude and orientation of cardiac vectors during the middle and terminal phase of activation. Rotation of the model heart around its longitudinal axis induces similar changes in the time course of the cardiac vector as are observed in some types of hypertrophy and in volume load of the ventricles.

UI	MeSH Term	Description	Entries
D008955	Models, Cardiovascular	Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.	Cardiovascular Model,Cardiovascular Models,Model, Cardiovascular
D003198	Computer Simulation	Computer-based representation of physical systems and phenomena such as chemical processes.	Computational Modeling,Computational Modelling,Computer Models,In silico Modeling,In silico Models,In silico Simulation,Models, Computer,Computerized Models,Computer Model,Computer Simulations,Computerized Model,In silico Model,Model, Computer,Model, Computerized,Model, In silico,Modeling, Computational,Modeling, In silico,Modelling, Computational,Simulation, Computer,Simulation, In silico,Simulations, Computer
D004594	Electrophysiology	The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.
D006321	Heart	The hollow, muscular organ that maintains the circulation of the blood.	Hearts
D006332	Cardiomegaly	Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.	Cardiac Hypertrophy,Enlarged Heart,Heart Hypertrophy,Heart Enlargement,Cardiac Hypertrophies,Enlargement, Heart,Heart Hypertrophies,Heart, Enlarged,Hypertrophies, Cardiac,Hypertrophies, Heart,Hypertrophy, Cardiac,Hypertrophy, Heart
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man