-transparent.png){kind=logo}
Two micronized oral formulations of medroxyprogesterone acetate (MPA) (Farlutal and Clinovir) were compared in order to evaluate their relative bioavailability. Sixteen female patients with metastatic breast cancer were entered in a randomized cross-over study on 500-mg MPA tablets repeatedly administered (twice daily for 20 days). At the steady state, similar mean +/- SD serum levels of MPA were obtained (131 +/- 44 ng/ml for Farlutal and 136 +/- 45 ng/ml for Clinovir) and the two formulations proved to be bioequivalent (confidence interval at a significance level of 0.95 = 93%-107%).
| UI | MeSH Term | Description | Entries |
|---|
Related Publications
K Pollow, and
R Kreienberg, and
N Di Pietro
January 2022,
Frontiers in veterinary science,
K Pollow, and
R Kreienberg, and
N Di Pietro
December 1990,
Arzneimittel-Forschung,
K Pollow, and
R Kreienberg, and
N Di Pietro
June 2013,
Contraception,
K Pollow, and
R Kreienberg, and
N Di Pietro
August 1986,
Chemioterapia : international journal of the Mediterranean Society of Chemotherapy,
K Pollow, and
R Kreienberg, and
N Di Pietro
January 1992,
Clinical therapeutics,
K Pollow, and
R Kreienberg, and
N Di Pietro
May 1992,
Farmaco (Societa chimica italiana : 1989),
K Pollow, and
R Kreienberg, and
N Di Pietro
June 1993,
Arzneimittel-Forschung,
K Pollow, and
R Kreienberg, and
N Di Pietro
January 1983,
Arzneimittel-Forschung,
K Pollow, and
R Kreienberg, and
N Di Pietro
February 1988,
Bollettino chimico farmaceutico,
K Pollow, and
R Kreienberg, and
N Di Pietro
June 2004,
International journal of clinical pharmacology and therapeutics,
