BIOMAT Database Logo BIOMAT Database Logo

Spontaneous germ-line ecotropic murine leukemia virus infection: implications for retroviral insertional mutagenesis and germ-line gene transfer. 1989

N G Copeland, and L F Lock, and S E Spence, and K J Moore, and D A Swing, and D J Gilbert, and N A Jenkins

UI MeSH Term Description Entries
D008815 Mice, Inbred Strains Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation. Inbred Mouse Strains,Inbred Strain of Mice,Inbred Strain of Mouse,Inbred Strains of Mice,Mouse, Inbred Strain,Inbred Mouse Strain,Mouse Inbred Strain,Mouse Inbred Strains,Mouse Strain, Inbred,Mouse Strains, Inbred,Strain, Inbred Mouse,Strains, Inbred Mouse
D009052 Leukemia Virus, Murine Species of GAMMARETROVIRUS, containing many well-defined strains, producing leukemia in mice. Disease is commonly induced by injecting filtrates of propagable tumors into newborn mice. Graffi Virus,Graffi's Chloroleukemic Strain,Leukemia Viruses, Murine,Mouse Leukemia Viruses,Murine Leukemia Virus,Murine Leukemia Viruses,Graffi Chloroleukemic Strain,Graffis Chloroleukemic Strain,Leukemia Viruses, Mouse
D009154 Mutation Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations. Mutations
D009865 Oocytes Female germ cells derived from OOGONIA and termed OOCYTES when they enter MEIOSIS. The primary oocytes begin meiosis but are arrested at the diplotene state until OVULATION at PUBERTY to give rise to haploid secondary oocytes or ova (OVUM). Ovocytes,Oocyte,Ovocyte
D004251 DNA Transposable Elements Discrete segments of DNA which can excise and reintegrate to another site in the genome. Most are inactive, i.e., have not been found to exist outside the integrated state. DNA transposable elements include bacterial IS (insertion sequence) elements, Tn elements, the maize controlling elements Ac and Ds, Drosophila P, gypsy, and pogo elements, the human Tigger elements and the Tc and mariner elements which are found throughout the animal kingdom. DNA Insertion Elements,DNA Transposons,IS Elements,Insertion Sequence Elements,Tn Elements,Transposable Elements,Elements, Insertion Sequence,Sequence Elements, Insertion,DNA Insertion Element,DNA Transposable Element,DNA Transposon,Element, DNA Insertion,Element, DNA Transposable,Element, IS,Element, Insertion Sequence,Element, Tn,Element, Transposable,Elements, DNA Insertion,Elements, DNA Transposable,Elements, IS,Elements, Tn,Elements, Transposable,IS Element,Insertion Element, DNA,Insertion Elements, DNA,Insertion Sequence Element,Sequence Element, Insertion,Tn Element,Transposable Element,Transposable Element, DNA,Transposable Elements, DNA,Transposon, DNA,Transposons, DNA
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012190 Retroviridae Family of RNA viruses that infects birds and mammals and encodes the enzyme reverse transcriptase. The family contains seven genera: DELTARETROVIRUS; LENTIVIRUS; RETROVIRUSES TYPE B, MAMMALIAN; ALPHARETROVIRUS; GAMMARETROVIRUS; RETROVIRUSES TYPE D; and SPUMAVIRUS. A key feature of retrovirus biology is the synthesis of a DNA copy of the genome which is integrated into cellular DNA. After integration it is sometimes not expressed but maintained in a latent state (PROVIRUSES). Leukemogenic Viruses,Leukoviruses,Oncornaviruses,Oncovirinae,Oncoviruses,Oncoviruses, Type C,RNA Tumor Viruses,Retroviruses,Type C Oncoviruses,C Oncovirus, Type,C Oncoviruses, Type,Leukemogenic Virus,Leukovirus,Oncornavirus,Oncovirus,Oncovirus, Type C,RNA Tumor Virus,Retrovirus,Tumor Virus, RNA,Tumor Viruses, RNA,Type C Oncovirus,Virus, Leukemogenic,Virus, RNA Tumor,Viruses, Leukemogenic,Viruses, RNA Tumor
D014162 Transfection The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES. Transfections
D051379 Mice The common name for the genus Mus. Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus

Related Publications

N G Copeland, and L F Lock, and S E Spence, and K J Moore, and D A Swing, and D J Gilbert, and N A Jenkins
Spontaneous germ line virus infection and retroviral insertional mutagenesis in eighteen transgenic Srev lines of mice.
January 1989, Molecular and cellular biology,
N G Copeland, and L F Lock, and S E Spence, and K J Moore, and D A Swing, and D J Gilbert, and N A Jenkins
Retroviral elements and their hosts: insertional mutagenesis in the mouse germ line.
January 2006, PLoS genetics,
N G Copeland, and L F Lock, and S E Spence, and K J Moore, and D A Swing, and D J Gilbert, and N A Jenkins
Retroviral insertional mutagenesis in murine mammary cancer.
October 1985, Proceedings of the Royal Society of London. Series B, Biological sciences,
N G Copeland, and L F Lock, and S E Spence, and K J Moore, and D A Swing, and D J Gilbert, and N A Jenkins
Retroviral insertional mutagenesis of a target allele in a heterozygous murine cell line.
October 1985, Proceedings of the National Academy of Sciences of the United States of America,
N G Copeland, and L F Lock, and S E Spence, and K J Moore, and D A Swing, and D J Gilbert, and N A Jenkins
Dynein Regulators Are Important for Ecotropic Murine Leukemia Virus Infection.
August 2016, Journal of virology,
N G Copeland, and L F Lock, and S E Spence, and K J Moore, and D A Swing, and D J Gilbert, and N A Jenkins
Insertional mutagenesis of preneoplastic astrocytes by Moloney murine leukemia virus.
April 2001, Journal of neurovirology,
N G Copeland, and L F Lock, and S E Spence, and K J Moore, and D A Swing, and D J Gilbert, and N A Jenkins
Ecotropic Murine Leukemia Virus Infection of Glial Progenitors Interferes with Oligodendrocyte Differentiation: Implications for Neurovirulence.
January 2016, Journal of virology,
N G Copeland, and L F Lock, and S E Spence, and K J Moore, and D A Swing, and D J Gilbert, and N A Jenkins
Gene transfer and genome-wide insertional mutagenesis by retroviral transduction in fish stem cells.
January 2015, PloS one,
N G Copeland, and L F Lock, and S E Spence, and K J Moore, and D A Swing, and D J Gilbert, and N A Jenkins
Retroviral insertional mutagenesis in murine promonocytic leukemias: c-myb and Mml1.
January 1996, Current topics in microbiology and immunology,
N G Copeland, and L F Lock, and S E Spence, and K J Moore, and D A Swing, and D J Gilbert, and N A Jenkins
Spontaneous tumors of NFS mice congenic for ecotropic murine leukemia virus induction loci.
August 1984, Journal of the National Cancer Institute,
Copied contents to your clipboard!